ArticleJournal of clinical hypertension (Greenwich, Conn.)2018
Frailty in Chinese older adults with hypertension: Prevalence, associated factors, and prediction for long-term mortality.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- The impact of depression on mortality among older adult patients with hypertension: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Global Prevalence and Factors Associated with Frailty among Community-Dwelling Older Adults with Hypertension: A Systematic Review and Meta-Analysis.The journal of nutrition, health & aging · 2023Pooled it
- Association between Frailty and Mortality, Falls, and Hospitalization among Patients with Hypertension: A Systematic Review and Meta-Analysis.BioMed research international · 2021Pooled it
- Effects of a 6-Month Educational Program on Blood Pressure in Pre-Frail and Frail Older Adults: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- The Association Between Urbanization and Frailty Status in China.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Prevalence and Predictors of Falls Among Younger and Older Adult Pilgrims During the Hajj Mass Gathering: An Age-Stratified Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Association of changes in frailty with mortality in the aged with hypertension.Scientific reports · 2025Article
- Nurse-Led Strategies for Lifestyle Modification to Control Hypertension in Older Adults: A Scoping Review.Nursing reports (Pavia, Italy) · 2025Review
- Article
- Prevalence and predictors of frailty among community-dwelling older adults with hypertension in China.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Association of frailty status with overall survival in elderly hypertensive patients: based on the Chinese Longitudinal Healthy Longevity Survey.BMC public health · 2024Article
- Interaction between hypertension and frailty and their impact on death risk in older adults: a follow-up study.BMC geriatrics · 2024Article
- Associations among frailty status, hypertension, and fall risk in community-dwelling older adults.International journal of nursing sciences · 2024Article
- Review
- Correlates of Frailty in Hospitalized Older Adults with Hypertension and Its Influence on Clinical Prognosis.International journal of general medicine · 2024Article
- Mediating effects of depression on sleep disturbance and frailty in older adult type 2 diabetes patients in the community.Frontiers in public health · 2023Article
- Prevalence of Hypertension and Its Association with Cardiovascular Risk Factors in College Students in Hunan, China.International journal of general medicine · 2023Article
- A study on the prevalence and related factors of frailty and pre-frailty in the older population with hypertension in China: A national cross-sectional study.Frontiers in cardiovascular medicine · 2022Article
- Evaluation of Frailty Syndrome and Adherence to Recommendations in Elderly Patients with Hypertension.Journal of clinical medicine · 2021Article
- Association of frailty with quality of life in older hypertensive adults: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension and frailty are associated and often coexist in older adults. Few studies have examined the association between hypertension and frailty in Chinese population. We explored the prevalence of and the factors associated with frailty as well as whether frailty could identify patients at risk of adverse outcomes among older adults with hypertension. Data were from the Beijing Longitudinal Study of Aging. A total of 1111 hypertensive participants aged ≥60 years old who completed the comprehensive geriatrics assessment were included. All participants were followed up for 8 years. The total number of deaths was 604. Frailty was assessed by the 68-item frailty index. Stepwise forward logistic regression was used to explore the association between the associated factors and frailty in hypertensive participants. The prediction for mortality was assessed using the adjusted Cox proportional hazards model. Two hundred and eighteen older adults were determined as frail (prevalence rate: 19.6%). Frail older adults with hypertension had worse physical performance, worse psychological, and social function, as well as worse lifestyle habits, compared to nonfrail older adults with hypertension. Chair stand test failure, balance test failure, fracture, disability, depression, and physical frailty measured with modified frailty phenotype were independently associated with frailty. Frailty was associated with a higher 8-year mortality, hazard ratio (HR) = 3.40, adjusted for age and sex, HR = 2.61. Frailty is associated with poorer physical function and higher mortality in community-dwelling hypertensive older adults in China. These findings emphasize the importance and need for frailty intervention and prevention in older adults with hypertension.
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