ArticleClinical cardiology2018
Association between ideal cardiovascular health and markers of subclinical cardiovascular disease.
Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cardiovascular Health, 2010 to 2020: A Systematic Review of a Decade of Research on Life's Simple 7.Journal of the American Heart Association · 2025Pooled it
- Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study.BMC medicine · 2021Pooled it
- Ultrasonic assessment of carotid intima-media thickness in migraine: a meta-analysis.The Journal of international medical research · 2019Pooled it
- 2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Midlife ICAM-1 levels may predict cardiovascular disease and cognitive decline in latelife: Insights from the HeartSCORE study.Atherosclerosis plus · 2025Article
- Does Music Experience Impact the Vascular Endothelial Response to Singing?Brain sciences · 2025Article
- Article
- Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function.Journal of the American Heart Association · 2024Article
- Association Between Cardiovascular Health and Subclinical Atherosclerosis Among Young Adults Using the American Heart Association's "Life's Essential 8" Metrics.Journal of the American Heart Association · 2024Article
- Association between cardiovascular health metrics and retinal ageing.GeroScience · 2023Article
- Associations between cumulative social risk, psychosocial risk, and ideal cardiovascular health: Insights from the HeartSCORE study.American journal of preventive cardiology · 2022Article
- Ideal Cardiovascular Health Metrics and Risk of Incident Early-Onset Vasomotor Symptoms Among Premenopausal Women.The Journal of clinical endocrinology and metabolism · 2022Article
- Association of ideal cardiovascular health with carotid intima-media thickness (cIMT) in a young adult population.Scientific reports · 2022Article
- Favorable Cardiovascular Health Is Associated With Lower Prevalence, Incidence, Extent, and Progression of Extracoronary Calcification: MESA.Circulation. Cardiovascular imaging · 2022Article
- Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021Review
- Further understanding of ideal cardiovascular health score metrics and cardiovascular disease.Expert review of cardiovascular therapy · 2021Review
- Therapeutic Features and Updated Clinical Trials of Mesenchymal Stem Cell (MSC)-Derived Exosomes.Journal of clinical medicine · 2021Review
- A bibliometric analysis of income and cardiovascular disease: Status, Hotspots, Trends and Outlook.Medicine · 2020Review
- Small but significant: Insights and new perspectives of exosomes in cardiovascular disease.Journal of cellular and molecular medicine · 2020Review
- Association of the Duration of Ideal Cardiovascular Health Through Adulthood With Cardiometabolic Outcomes and Mortality in the Framingham Offspring Study.JAMA cardiology · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundIdeal cardiovascular health (CVH) was proposed by the American Heart Association to promote population health. We aimed to characterize the association between ideal CVH and markers of subclinical cardiovascular disease (CVD). HYPOTHESIS: We hypothesized that ideal CVH is associated with several markers of subclinical CVD.
methodsWe used data from the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) study. We assigned 1 for each of the ideal CVH factors met. Endothelial function, expressed as Framingham reactive hyperemia index (fRHI), was measured using the EndoPAT device. Coronary artery calcium (CAC) and carotid intima-media thickness (CIMT) were quantified using electron beam computed tomography and carotid ultrasonography, respectively.
resultsA total of 1933 participants (mean [SD] age: 59 [7.5] years, 34% male, 44% black) were included. The mean number of ideal CVH factors met was 2.3 ± 1.3, with blacks having significantly lower score compared to whites (2.0 ± 1.2 vs 2.5 ± 1.4, respectively; P < 0.001). Seven hundred and eighty-nine participants (41%) achieved ≥3 ideal CVH factors. Participants with ≥3 ideal CVH factors (compared to those with <3 factors) had an average of 107 (95% confidence interval [CI]: 50-165) Agatston units lower CAC, 0.04 (0.01-0.06) mm lower CIMT, and 0.07 (0.02-0.12) units higher fRHI, after adjusting for age, sex, race, income, education, and marital status. Participants with ≥3 ideal CVH factors had 50% lower odds (95% CI: 28%-66%) of having CAC >100 Agatston units.
conclusionIn a community-based study with low prevalence of ideal CVH, even achieving three or more ideal CVH factors were associated with lower burden of subclinical CVD, indicating the utility of this construct for disease prevention.
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