ArticleCell2018
Statistical Detection of Relatives Typed with Disjoint Forensic and Biomedical Loci.
Article in Cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Toward minimal SNP sets for record-matching with CODIS STR profiles.European journal of human genetics : EJHG · 2026Article
- DNA Mixture Deconvolution: A Four-Strategy Framework from Physical Separation to Database Searching.Genes · 2026Review
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- Assessing Privacy Vulnerabilities in Genetic Data Sets: Scoping Review.JMIR bioinformatics and biotechnology · 2024Article
- Solving the Arizona search problem by imputation.iScience · 2024Article
- Record-matching of STR profiles with fragmentary genomic SNP data.European journal of human genetics : EJHG · 2023Article
- Microsatellites used in forensics are in regions enriched for trait-associated variants.iScience · 2023Article
- Microsatellites used in forensics are located in regions unusually rich in trait-associated variants.bioRxiv : the preprint server for biology · 2023Article
- Gattaca as a lens on contemporary genetics: marking 25 years into the film's "not-too-distant" future.Genetics · 2022Article
- Associations between forensic loci and expression levels of neighboring genes may compromise medical privacy.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Sociotechnical safeguards for genomic data privacy.Nature reviews. Genetics · 2022Review
- Using game theory to thwart multistage privacy intrusions when sharing data.Science advances · 2021Article
- Article
- Article
- Forensic genealogy, bioethics and the Golden State Killer case.Forensic science international. Synergy · 2019Article
- When Biology Gets Personal: Hidden Challenges of Privacy and Ethics in Biological Big Data.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
In familial searching in forensic genetics, a query DNA profile is tested against a database to determine whether it represents a relative of a database entrant. We examine the potential for using linkage disequilibrium to identify pairs of profiles as belonging to relatives when the query and database rely on nonoverlapping genetic markers. Considering data on individuals genotyped with both microsatellites used in forensic applications and genome-wide SNPs, we find that ∼30%-32% of parent-offspring pairs and ∼35%-36% of sib pairs can be identified from the SNPs of one member of the pair and the microsatellites of the other. The method suggests the possibility of performing familial searches of microsatellite databases using query SNP profiles, or vice versa. It also reveals that privacy concerns arising from computations across multiple databases that share no genetic markers in common entail risks, not only for database entrants, but for their close relatives as well.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.