Evidence map›Paper›PMID 30317799›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2018

[Research progress of receptor targeted hepatic stellate cell in treatment of liver fibrosis].

D Yang

Open access · greenAbstract readReview
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. [Role of CXCL12-CXCR4/CXCR7 signal axis in liver regeneration and liver fibrosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Article
  3. Article
  4. Antiliver Fibrosis Screening of Active Ingredients fromEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

D YangDepartment of Specific Diagnosis, PLA 324th Hospital, Chongqing 400020, China.
82th Hospital of Pla · CN

Funding

Natural Science Foundation of Chongqing cstc2013jcyjA10065
6 · The paper itself

Abstract

Liver fibrosis is a major public health problem with high morbidity and mortality rate. Despite noteworthy progress in understanding the mechanisms of liver fibrosis, anti-hepatic fibrosis treatments have partial efficacy. The main reason is failure of transported target drug into the target cells, resulting in insufficient concentration of target drugs, and the side effects caused by non-target cells are large. Activation and proliferation of hepatic stellate cell is a key link in the progression of liver fibrosis. Therefore, one of the main goals of anti-fibrotic therapy is to develop a drug delivery system targeting hepatic stellate cells to efficiently target drugs in active hepatic stellate cells without affecting other organs and other cells in the liver. In this review, we outline a number of receptor-mediated strategies for targeting drug delivery in hepatic stellate cells.

Indexed as

Hepatic Stellate CellsDisease ProgressionHumansKupffer CellsLiverLiver CirrhosisHepatic stellate cellsLiver fibrosisReceptors

Identifiers

PMID30317799
PMCPMC12770575
OpenAlexW2991109189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.