Evidence map›Paper›PMID 30317488›Full record

ArticleObesity surgery2019

Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass.

Ryan D Horsley, Ellen D Vogels, Daaron A P McField, David M Parker, Charles Medico, James Dove, Marcus Fluck, Jon D Gabrielsen, Michael R Gionfriddo, Anthony T Petrick

Abstract read
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In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ryan D HorsleyDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA. rdhorsley@geisinger.edu.ORCID 0000-0002-6125-0674
Ellen D VogelsDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Daaron A P McFieldDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
David M ParkerDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Charles MedicoEnterprise Pharmacy, Geisinger, 100 North Academy Ave, Danville, PA, 17822, USA.
James DoveDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Marcus FluckDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Jon D GabrielsenDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Michael R GionfriddoCenter for Pharmacy Innovation and Outcomes, Geisinger, 190 Welles Street, Suite 128, Forty Fort, PA, USA.
Anthony T PetrickDivision of Bariatric and Foregut Surgery, Geisinger Medical Center, 100 North Academy Ave, Danville, PA, 17822, USA.
Geisinger Medical Center · USCenter for Innovation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpioids have been the mainstay for postoperative pain relief for many decades. Recently, opioid-related adverse events and death have been linked to postoperative dependency. Multimodal approaches to postoperative pain control may be part of the solution to this health care crisis. The safety and effectiveness of multimodal pain control regimens after laparoscopic Roux-en-Y gastric bypass (LRYGB) has not been well studied. The primary aim of our study was to determine if an evidence-based, multimodal pain regimen during hospitalization could decrease the total oral morphine equivalent (TME) use after LRYGB. STUDY

designWe conducted a retrospective cohort study comparing outcomes prior to the implementation of a multimodal pain protocol (December 2010-December 2012) to those after implementation (April 2013-July 2015). The protocol utilized oral celecoxib and scheduled oral acetaminophen for pain control, with opioids used only as needed for breakthrough pain. Data was extracted from an electronic medical record and an institutionally maintained database of all patients undergoing bariatric surgery at a single center.

resultsCompared to controls, the multimodal pain regimen significantly reduced TME used and maximum pain scores with no change in mean pain scores. Multimodal pain protocol patients had a shorter length of stay with no increase in bleeding complications or marginal ulcer rates.

conclusionsAn opioid-sparing multimodal pain regimen adequately controls pain while reducing TME use. The regimen appears to be safe and was associated with a reduced length of stay in patients undergoing LRYGB.

Indexed as

AcetaminophenAdministration, OralAdultAgedAnalgesics, OpioidBreakthrough PainCelecoxibDose-Response Relationship, DrugDrug Therapy, CombinationFemaleGastric BypassHumansLaparoscopyMaleMiddle AgedObesity, MorbidAcetaminophenAnalgesics, OpioidCelecoxibAcetaminophenBariatric surgeryCelecoxibMultimodal pain controlOpioid

Identifiers

PMID30317488
OpenAlexW2897833624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.