Evidence map›Paper›PMID 30317468›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2019

Vitamin D levels and fracture risk among Hispanic children.

Norman Ramirez, Jose L Ortiz-Fullana, Norma Arciniegas, Altagracia Fullana, Pablo Valentin, Juan Carlos Orengo, Ivan Iriarte, Simon Carlo

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04564625 (Relationships Between Vitamin D and Orthopedic Trauma), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04564625 completednot on this mapstarted 2020, after this paper: background citation

Relationships Between Vitamin D and Orthopedic Trauma

TypeobservationalSponsorMethodist Health SystemRan2020 to 2021Enrolled100ConditionsFracture, Fracture Nonunion, Fractures, Bone, Vitamin DArmsVitamin D Assessment, Fracture
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Association of serum 25(OH)Vit-D levels with risk of pediatric fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
  3. Article
  4. Low Vitamin D Levels Are Associated With Longer Healing Times in Pediatric Fracture Patients.Journal of the Pediatric Orthopaedic Society of North America · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Norman RamirezMayaguez Medical Center, Box 6847, Mayaguez, 00680, Puerto Rico. normanpipe@aol.com.ORCID http://orcid.org/0000-0002-7254-6059
Jose L Ortiz-FullanaUniversidad Central del Caribe, Bayamon, 00960, Puerto Rico.
Norma ArciniegasMayaguez Medical Center, Box 6847, Mayaguez, 00680, Puerto Rico.
Altagracia FullanaManati Medical Center, Manati, 00674, Puerto Rico.
Pablo ValentinInterAmerican University, San German, 00683, Puerto Rico.
Juan Carlos OrengoPonce Health Sciences University, Ponce, 00732, Puerto Rico.
Ivan IriartePonce Health Sciences University, Ponce, 00732, Puerto Rico.
Simon CarloMayaguez Medical Center, Box 6847, Mayaguez, 00680, Puerto Rico.
Ponce Health Sciences University · PRMayagüez Medical CenterCentral University of the Caribbean · PRInterAmerican University of Puerto Rico · PRUniversity of Puerto Rico, Medical Sciences Campus · PR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a lack of knowledge about whether low vitamin D levels increase the risk of pediatric low-energy fractures among Hispanic population. The objective of this study is to determine whether there is a direct relationship between low vitamin D levels and the incidence of low-energy fractures in Hispanic children.

methodCases included all consecutive patients evaluated with low-energy fractures in the pediatric orthopedic clinic. The control group consisted of all pediatric patients evaluated, without fractures, who had bone and joint pain complaints in the general pediatric clinic. The main focus was to compare cases and controls in relation to their vitamin D levels. Cases and controls were compared using t tests for means of quantitative variables and Chi-square tests.

resultsA total of 201 subjects, distributed as cases (n = 107) and controls (n = 94), were included in this study. One hundred twelve (55.7%) of the total study population were males. The mean age for the study population was 8.6 years old ranging from 1 year to 18 years, and standard deviation = 4.0 years. The median age for the study population was 9 years. The mean vitamin D level for the cases was 32.6 ng/dl (SD = 10.9); the mean vitamin D level for controls was 32.3 ng/dl (SD = 13.4). This difference was not statistically significant (t = 0.18, 95% CI - 3.2 to 3.9; p = 0.854).

conclusionA direct relationship between low vitamin D levels and fracture risk in a Hispanic pediatric population was not established. LEVELS OF EVIDENCE: III.

Indexed as

AdolescentAlkaline PhosphataseCase-Control StudiesChildChild, PreschoolFemaleFractures, BoneHumansIncidenceInfantMaleParathyroid HormonePuerto RicoVitamin D25-hydroxyvitamin DAlkaline PhosphataseParathyroid HormoneVitamin DFracture risksHispanic populationVitamin D

Identifiers

PMID30317468
OpenAlexW2901717281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.