Evidence map›Paper›PMID 30317418›Full record

ReviewCurrent allergy and asthma reports2018

IgE Test in Secretions of Patients with Respiratory Allergy.

Carmen Rondón, Ibon Eguíluz-Gracia, Mohamed H Shamji, Janice A Layhadi, María Salas, María José Torres, Paloma Campo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. A Clinical Approach of Allergic Rhinitis in Children.Children (Basel, Switzerland) · 2023
    Review
  4. Review
  5. Atopy in Kashmir-validation from a case control study with respect to IgE and Interleukin genes.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
  6. Article
  7. Review
  8. Diagnostic Tools in Allergic Rhinitis.Frontiers in allergy · 2021
    Review
  9. Review
  10. Article
  11. Local Allergic Rhinitis Revisited.Current allergy and asthma reports · 2020
    Review
  12. Allergen Immunotherapy for Local Respiratory Allergy.Current allergy and asthma reports · 2020
    Review
  13. EAACI Allergen Immunotherapy User's Guide.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2020
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Carmen RondónAllergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain.
Ibon Eguíluz-GraciaAllergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain.
Mohamed H ShamjiImmunomodulation and Tolerance Group, Allergy and Clinical Immunology, Inflammation, Repair and Development, MRC Asthma UK Centre Imperial College London, London, UK.
Janice A LayhadiImmunomodulation and Tolerance Group, Allergy and Clinical Immunology, Inflammation, Repair and Development, MRC Asthma UK Centre Imperial College London, London, UK.
María SalasAllergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain.
María José TorresAllergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain.
Paloma CampoAllergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain. campomozo@gmail.com.
Hospital Regional Universitario de Málaga · ESAsthma UK · GBInstituto de Investigación Biomédica de Málaga · ES

Funding

Medical Research Council G1000758
6 · The paper itself

Abstract

purpose of reviewIgE is a key player in multiple inflammatory airway diseases. Ample literature demonstrates its presence in mucosa of patients with allergic rhinitis (AR), local allergic rhinitis (LAR), asthma, or chronic rhinosinusitis with nasal polyposis (CRSwNP). RECENT

findingsCurrent evidence shows that high-affinity IgE in blood stream of allergic individuals derives mainly from the mucosae. Also, mucosal synthesis of IgE can occur in the absence of systemic atopy, and may be relevant in atopic and non-atopic phenotypes of rhinitis as demonstrated in LAR. Specific IgE (sIgE) detection varies depending on technique used for sample collection and its measurement. sIgE detection is highly specific for diagnosis of LAR. Moreover, measurement of sIgE in secretions could be useful in monitoring response to allergen-specific immunotherapy in both AR and LAR phenotypes. This review will focus on recent developments in the role of IgE in respiratory diseases, and the clinical implications of its measurement in secretions.

Indexed as

Bodily SecretionsDiagnostic Techniques and ProceduresHumansImmunoglobulin ERespiratory MucosaRhinitis, AllergicImmunoglobulin EAllergen-specific immunotherapyAllergicIgELocal allergic rhinitisRhinitis

Identifiers

PMID30317418
OpenAlexW2896972169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.