Evidence map›Paper›PMID 30317207›Full record

ArticleBMJ case reports2018

Large endotracheal tumour presenting as severe COPD: flow-volume loop analysis, not always a straightforward diagnostic test.

Iliya P Amaza, Swan Lee, Rolando Sanchez

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Iliya P AmazaDepartment of Internal Medicine - Division of Pulmonary and Critical Care Medicine, University of Iowa - Carver College of Medicine, Iowa City, IA, USA.ORCID http://orcid.org/0000-0002-0498-6896
Swan LeeDepartment of Internal Medicine, University of Chicago (NorthShore), Evanston, IL, USA.
Rolando SanchezDepartment of Internal Medicine - Division of Pulmonary and Critical Care Medicine, University of Iowa - Carver College of Medicine, Iowa City, IA, USA.
University of Iowa · USNorthShore University HealthSystem · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The flow-volume loop (FVL) analysis is typically helpful in establishing the diagnosis of airway obstruction caused by endobronchial lesions. In this report, we describe a patient with emphysema and tobacco abuse who presented with chronic dry cough and severe chronic obstructive pulmonary disease (COPD) refractory to standard therapy. The initial FVL showed a relatively normal forced expiratory peak flow shape followed by a smooth flattening of the expiratory curve on spirometry, a pattern consistent with distal airway obstruction as seen in severe asthma or COPD. The patient was later found to have a large endotracheal mass. This atypical presentation, along with the unusual FVL, led to a significant delay in the diagnosis of the tracheal mass. A high level of suspicion is needed to diagnose variable intrathoracic airway obstruction in patients presenting with severe asthma or COPD who fail to improve with standard therapy.

Indexed as

EmphysemaSmokingAirway ObstructionChoroid NeoplasmsDiagnosis, DifferentialFemaleHumansMelanomaMiddle AgedNeoplasm MetastasisPulmonary Disease, Chronic ObstructiveSpirometryTomography, X-Ray ComputedTracheal Neoplasmslung functionrespiratory cancerrespiratory medicine

Identifiers

PMID30317207
PMCPMC6194418
OpenAlexW2898041580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.