Evidence map›Paper›PMID 30317162›Full record

SynthesisDrug and alcohol dependence2018

Effects of neuromodulation on cognitive performance in individuals exhibiting addictive behaviors: A systematic review.

Katherine R Naish, Lana Vedelago, James MacKillop, Michael Amlung

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. [Quantitative analysis of transcranial temporal interference stimulation in rodents: A simulation study on electrode configurations].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cognition and addiction
.Dialogues in clinical neuroscience · 2019
    Review
  19. Computational psychiatry of impulsivity and risk: how risk and time preferences interact in health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Katherine R NaishPeter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton and McMaster University, 100 West 5th Street, Hamilton, Ontario, L8P 3R2, Canada. Electronic address: naishek@mcmaster.ca.
Lana VedelagoPeter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton and McMaster University, 100 West 5th Street, Hamilton, Ontario, L8P 3R2, Canada. Electronic address: lvedelag@stjosham.on.ca.
James MacKillopPeter Boris Centre for Addictions Research, Michael G. DeGroote Centre for Medicinal Cannabis Research, St. Joseph's Healthcare Hamilton and McMaster University, 100 West 5th Street, Hamilton, Ontario, L8P 3R2, Canada. Electronic address: jmackill@mcmaster.ca.
Michael AmlungPeter Boris Centre for Addictions Research, Michael G. DeGroote Centre for Medicinal Cannabis Research, St. Joseph's Healthcare Hamilton and McMaster University, 100 West 5th Street, Hamilton, Ontario, L8P 3R2, Canada. Electronic address: amlungm@mcmaster.ca.
St. Joseph’s Healthcare Hamilton · CA

Funding

Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African AmericansP30DA027827 · NIDA · UNIVERSITY OF GEORGIA · PI BRODY, GENE H. · 2009 to 2018
$10.2M
The role of religiosity, socioeconomic status and the relationship between behavioral economic variables as mediators of negative alcohol-related consequences in African American emerging adultsR01AA024930 · NIAAA · UNIVERSITY OF MEMPHIS · PI MACKILLOP, JAMES, MURPHY, JAMES G. · 2017 to 2021
$1.6M
NIAAA NIH HHS R01 AA024930NIDA NIH HHS P30 DA027827
6 · The paper itself

Abstract

backgroundThere is growing interest in non-invasive brain stimulation techniques as treatments for addictive disorders. While multiple reviews have examined the effects of neuromodulation on craving and consumption, there has been no review of how neuromodulation affects cognitive functioning in addiction. This systematic review examined studies of the cognitive effects of transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) in individuals exhibiting addictive behavior.

methodsArticles were identified through searches in PubMed and PsycINFO conducted in October 2017. Eligible studies investigated the effects of tDCS or TMS on cognitive task performance in participants reporting substance use (e.g., alcohol, tobacco, or drugs) or addictive behaviors (e.g., gambling). Tasks were organized into five domains: (1) Inhibitory control, (2) Risk-taking, (3) Impulsive choice (delay discounting), (4) Executive function, and (5) Implicit biases.

resultsTwenty-four articles met the inclusion criteria. Fifty-seven percent of studies used tDCS and 43% used TMS, with nearly all studies (96%) targeting the dorsolateral prefrontal cortex. Ten studies reported significant within-subject modulation of cognitive functioning associated with active TMS or tDCS, with the same number reporting no change in cognitive performance. Of four studies that included both an experimental and control participant group, three showed between-group differences in the effects of neuromodulation.

conclusionsWhile positive effects in several studies suggest that tDCS and TMS improve cognitive functioning in addiction, there is substantial heterogeneity across studies. We discuss person-related and methodological factors that could explain inconsistencies, and propose individualized stimulation protocols may sharpen the cognitive effects of neuromodulation in addiction.

Indexed as

AdultBehavior, AddictiveCognitionCravingExecutive FunctionFemaleGamblingHumansImpulsive BehaviorMalePrefrontal CortexTranscranial Direct Current StimulationTranscranial Magnetic StimulationTreatment OutcomeAddictionBrain stimulationCognitionSubstance useTranscranial direct current stimulationTranscranial magnetic stimulation

Identifiers

PMID30317162
PMCPMC8995136
OpenAlexW2895503081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.