Evidence map›Paper›PMID 30316809›Full record

Observational studyJournal of pain and symptom management2019

Factors Related to Adherence to Opioids in Black Patients With Cancer Pain.

Katherine A Yeager, Bryan Williams, Jinbing Bai, Hannah L F Cooper, Tammie Quest, Salimah H Meghani, Deborah W Bruner

Abstract readObservational Study
In one paragraph

Observational study in Journal of pain and symptom management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pain among older adults with gastrointestinal malignancies- results from the cancer and aging resilience evaluation (CARE) Registry.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  10. Pain, depressive symptoms, and self-efficacy for pain management: examination in African-American women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Factors Associated with Depression in African American Patients Being Treated for Cancer Pain.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2020
    Article
  18. Article
  19. Both Race and Insurance Type Independently Predict the Selection of Oral Opioids Prescribed to Cancer Outpatients.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine A YeagerNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA; Winship Cancer Institute, Emory University, Atlanta, Georgia, USA. Electronic address: kyeager@emory.edu.
Bryan WilliamsNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Jinbing BaiNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Hannah L F CooperRollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Tammie QuestSchool of Medicine, Emory University, Atlanta, Georgia, USA.
Salimah H MeghaniSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Deborah W BrunerNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA; Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Adherence in African Americans Being Treated for Cancer Pain K01NR014673 · NINR · EMORY UNIVERSITY · PI YEAGER, KATHERINE AYLWARD · 2013 to 2015
$275k
NCATS NIH HHS UL1 TR000445NIAID NIH HHS P30 AI050409NINR NIH HHS K01 NR014673
6 · The paper itself

Abstract

contextCancer pain relief is often inadequate because of poor adherence to pain medication, especially for black patients.

objectivesThe purpose of this study is to describe factors related to adherence to around-the-clock opioids among 110 black patients being treated for cancer pain.

methodsSociodemographic, clinical, symptoms, and social support data were collected at baseline; pain and adherence data were collected at 30 days. Associations between these variables and opioid adherence measured by Medication Event Monitoring System were estimated using multiple regression.

resultsMean age was 56 (±10.1), the majority were women (63%) and college educated (56%). Mean pain severity at baseline equaled 4.6 (±2.3). Mean dose adherence was 60% (±28.5), while mean schedule adherence was 33.0% (±31.0). In adjusted analysis, 26% of the variance in dose adherence was explained by recent chemotherapy, changes in pain, concerns about nausea, and doctors' focus on cure versus pain control (P<0.001); 27% of the variance in schedule adherence was explained by recent chemotherapy, changes in pain, symptom burden, and concerns about doctors focus on cure versus pain control (P<0.001).

conclusionFindings confirm pain medication adherence is poor and pain was not well relieved. Multiple factors influence adherence to around-the-clock opioids. Clinicians need to partner with patients by providing a personalized pain treatment plan including an in-depth assessment of treatment choices and adherence.

Indexed as

Black or African AmericanAnalgesics, OpioidCancer PainFemaleFollow-Up StudiesHumansMaleMedication AdherenceMiddle AgedPain ManagementPalliative CareProspective StudiesSocial SupportAnalgesics, OpioidadherenceBlack raceCancer painelectronic monitoringopioids

Identifiers

PMID30316809
PMCPMC6310640

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.