ReviewJournal of assisted reproduction and genetics2019
The role of microRNAs in human embryo implantation: a review.
Review in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Optimal timing to transfer embryos for women who underwent hysteroscopy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- MicroRNA Associations with Preterm Labor-A Systematic Review.International journal of molecular sciences · 2024Pooled it
- The molecular puzzle of recurrent implantation failure: integrating genetic, epigenetic, and immune mechanisms for precision reproductive medicine.Journal of assisted reproduction and genetics · 2026Review
- Pathway-Level Convergence Between Dynamic Plasma miRNAs and Endometrial Biological Processes During the Human Peri-Implantation Window.International journal of molecular sciences · 2026Article
- Placental miRNA profiling in assisted reproductive technology (ART) pregnancies.Journal of assisted reproduction and genetics · 2025Article
- Extracellular vesicles: key mediators inFrontiers in veterinary science · 2025Review
- Effects of acupuncture and moxibustion therapy on endometrial receptivity of infertile women withFrontiers in medicine · 2025Review
- Decreased expression ofInternational journal of reproductive biomedicine · 2024Article
- Investigating the Imperative Role of microRNAs Expression in Human Embryo Implantation: A Narrative Review Based on Recent Evidence.Biomedicines · 2024Review
- The role of viral infection in implantation failure: direct and indirect effects.Reproductive biology and endocrinology : RB&E · 2024Review
- MiRNAs related in signaling pathways of women's reproductive diseases: an overview.Molecular biology reports · 2024Review
- lncRNA TTTY14 participates in the progression of repeated implantation failure by regulating the miR-6088/SEMA5A axis.Journal of assisted reproduction and genetics · 2024Article
- A validated model for individualized prediction of pregnancy outcome in woman after fresh cycle of Day 5 single blastocyst transfer.Scientific reports · 2023Article
- MicroRNAs, small regulatory elements with significant effects on human implantation: a review.Journal of assisted reproduction and genetics · 2023Review
- microRNAs as A Biomarker to Predict Embryo Quality Assessment in In Vitro Fertilization.International journal of fertility & sterility · 2023Article
- Dynamic peripheral blood microRNA expression landscape during the peri-implantation stage in women with successful pregnancy achieved by single frozen-thawed blastocyst transfer.Human reproduction open · 2023Article
- MicroRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation.International journal of molecular sciences · 2022Review
- Epigenetics of pregnancy: looking beyond the DNA code.Journal of assisted reproduction and genetics · 2022Review
- Oocyte aging: looking beyond chromosome segregation errors.Journal of assisted reproduction and genetics · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are emerging as important in human embryo implantation, and we present here a review of the literature from a clinical perspective. Implantation involves complex interactions between the blastocyst and endometrium. miRNAs have been shown to be differentially expressed in implanted compared with non-implanted blastocysts and euploid compared with aneuploid blastocysts. Further, miRNAs are differentially expressed in proliferative compared with decidualized endometrium, and in receptive compared with pre-receptive endometrium. miRNAs are also differentially expressed in endometrium of women who failed implantation, and in endometrium of women with recurrent implantation failure. Due to the complexity of miRNA signaling, studies have suffered from inconsistency in reproducibility of results. However, miRNAs show potential as biomarkers in the pursuit of more reliable prediction of embryo implantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.