ReviewPharmacoEconomics2019
The Economic Burden of Pediatric Asthma in the United States: Literature Review of Current Evidence.
Review in PharmacoEconomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 6 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- The Clinical and Economic Impact of Biologic Agents in Asthma Management: a Systematic Review.Lung · 2026Pooled it
- Vitamin D supplementation in pregnant or breastfeeding women or young children for preventing asthma.The Cochrane database of systematic reviews · 2025Pooled it
- Intravenous Bronchodilators in Pediatric Critical Asthma: A Systematic Review and Network Meta-Analysis.Pediatric pulmonology · 2025Pooled it
- Effects of probiotics, prebiotics, synbiotics and postbiotics on pediatric asthma: a systematic review.Frontiers in nutrition · 2025Pooled it
- Non-invasive positive pressure ventilation for acute asthma in children.The Cochrane database of systematic reviews · 2024Pooled it
- Pulmonary Health Effects of Indoor Volatile Organic Compounds-A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Bilevel Positive Airway Pressure and Continuous Albuterol for Pediatric Asthma Exacerbations: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Sociodemographic Differences in Asthma Self-Management Knowledge of Parents Seeking Asthma Care for their Children in Pediatric Emergency Departments.Journal of health care for the poor and underserved · 2021Trial
- Text2Breathe: Text-Message Intervention for Parent Communication and Pediatric Asthma.Academic pediatricsTrial
- Timing of High-Risk Asthma Specialist Enrollment and Severe Asthma Exacerbations in Children.The journal of allergy and clinical immunology. In practice · 2026Article
- Current Practices and Variations Among Pediatric Severe Asthma Programs in the United States-The North American Severe Pediatric Asthma Consortium.Pediatric pulmonology · 2026Observational
- Caregiver Empowerment of Children With Asthma: A Literature Review.Journal for specialists in pediatric nursing : JSPN · 2026Review
- The Burden of Laryngeal Cleft in Children With Refractory Asthma: A 10-Year Multicenter Experience.Pediatric pulmonology · 2026Observational
- Real-world impact of mepolizumab on pediatric and adolescent patients with severe asthma.The journal of allergy and clinical immunology. Global · 2026Article
- Determinants of Asthma Control in Jordanian Children: The Role of Comorbidities and FeNO Levels.Children (Basel, Switzerland) · 2025Article
- Benefits and Barriers of Caregiver App Engagement for Supporting Diverse Children With Asthma: Mixed Methods Study.JMIR pediatrics and parenting · 2025Article
- Socioeconomic disparities in inpatient outcomes among US pediatric asthma hospitalizations.Respiratory medicine · 2025Article
- Article
- Asthma Phenotype Progression in Children and Adolescents: A Single Center Experience.Pediatric pulmonology · 2025Article
- The Airport, Air Quality and Asthma (AAA) Indoor Air Intervention Trial for Children with Asthma: Protocol for a Community Based Study in South King County, Washington State.Research square · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a chronic respiratory disease that is widespread throughout the US population and disproportionately affects children. This literature review aimed to identify recent information regarding the economic burden of pediatric asthma in the US. MEDLINE, EMBASE, Econlit, and PsycINFO databases and gray literature sources were searched from January 2012 to January 2018 to capture relevant publications. Publications reporting on healthcare resource utilization and/or healthcare costs of pediatric asthma were included (n = 8). Total direct costs of pediatric asthma were US$5.92 billion in 2013. Average annual costs per child ranged from US$3076 to US$13612. Across studies, pharmacy (US$1027-2120), inpatient (US$337-2016) and outpatient (US$1049-8039) costs were the primary contributors to healthcare costs. Inpatient and emergency department (ED) visits exerted a high economic burden. For instance, the national annual cost of asthma-related hospitalizations was estimated at US$1.59 billion in 2009, while estimates of costs-per-hospitalization (2010) and charges-per-discharge (2009) were US$3600 and US$8406, respectively. The total cost of ED visits to Medicaid was estimated at US$272 million in 2010. In a mixed-insurance population, ED cost estimates ranged from US$152 to US$172 annually per patient. Invariably, costs for children with asthma were significantly greater than for children without. Pediatric asthma imposes a significant economic burden to the US healthcare system. Children with asthma have significantly higher healthcare resource utilization and costs than children without asthma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.