Evidence map›Paper›PMID 30315404›Full record

ArticleTranslational stroke research2019

Brain Ceruloplasmin Expression After Experimental Intracerebral Hemorrhage and Protection Against Iron-Induced Brain Injury.

Hongwei Liu, Ya Hua, Richard F Keep, Guohua Xi

Open access · greenAbstract read
In one paragraph

Article in Translational stroke research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. A new spectrophotometric method for measuring ceruloplasmin ferroxidase activity: an innovative approach.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  9. Mechanisms of cuproptosis and its relevance to distinct diseases.Apoptosis : an international journal on programmed cell death · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Endogenous FGF21 attenuates blood-brain barrier disruption in penumbra after delayed recanalization in MCAO rats through FGFR1/PI3K/Akt pathway.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  17. Review
  18. The Role of Ferroptosis in Blood-Brain Barrier Injury.Cellular and molecular neurobiology · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hongwei LiuDepartment of Neurosurgery, R5018 BSRB, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Ya HuaDepartment of Neurosurgery, R5018 BSRB, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Richard F KeepDepartment of Neurosurgery, R5018 BSRB, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Guohua XiDepartment of Neurosurgery, R5018 BSRB, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. guohuaxi@umich.edu.
University of Michigan–Ann Arbor · USXiangya Hospital Central South University · CN

Funding

Early hematoma lysis and hemoglobin toxicity in intracerebral hemorrhageR01NS106746 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KEEP, RICHARD F · 2018 to 2022
$2.5M
Iron, minocycline and brain injury after intracerebral hemorrhageR01NS090925 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2015 to 2019
$1.7M
Targeting CD47 to aid in clearing intracerebral hemorrhagesR01NS096917 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUA, YA, XI, GUOHUA · 2016 to 2020
$1.7M
Mechanisms of Brain Injury after Intraventricular HemorrhageR01NS073595 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2012 to 2016
$1.7M
Mechanisms of early brain injury after subarachnoid hemmorrhageR01NS079157 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2012 to 2016
$1.7M
Lipocalin-2 and Intracerebral Hemorrhage-induced Brain InjuryR21NS091545 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUA, YA · 2015 to 2016
$427k
NINDS NIH HHS R01 NS073595NINDS NIH HHS R01 NS079157NINDS NIH HHS R01 NS090925NINDS NIH HHS R01 NS096917NINDS NIH HHS R01 NS106746NINDS NIH HHS R21 NS091545
6 · The paper itself

Abstract

Ceruloplasmin (CP) is an essential ferroxidase that is involved in maintaining iron homeostasis by oxidizing toxic ferrous iron (Fe

Indexed as

Analysis of VarianceAnimalsAstrocytesBrainBrain InjuriesCalcium-Binding ProteinsCell DeathCerebral HemorrhageCeruloplasminDisease Models, AnimalDopamine and cAMP-Regulated Phosphoprotein 32Gene Expression RegulationIn Situ Nick-End LabelingIronMagnetic Resonance ImagingMaleAif1 protein, ratCalcium-Binding ProteinsCeruloplasminDopamine and cAMP-Regulated Phosphoprotein 32IronMicrofilament ProteinsPhosphopyruvate HydrataseBlood-brain barrier disruptionCerebral hemorrhageCeruloplasminIronNeuronal death

Identifiers

PMID30315404
PMCPMC6438204
OpenAlexW2897400127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.