Evidence map›Paper›PMID 30315375›Full record

ReviewCurrent treatment options in neurology2018

Treatment of Persistent Postural-Perceptual Dizziness (PPPD) and Related Disorders.

Stoyan Popkirov, Jon Stone, Dagny Holle-Lee

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07420803 (Efficacy Of Auricular Transcutaneous Vagus Nerve Stimulation In Treating Chronic Dizziness), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07420803 narecruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy Of Auricular Transcutaneous Vagus Nerve Stimulation In Treating Chronic Dizziness

TypeinterventionalSponsorMayo ClinicRan2026 to 2027Enrolled60ConditionsChronic Dizziness, Persistent Postural Perceptual DizzinessArmsSham Device, Auricular transcutaneous vagus nerve stimulation
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 123 citations in OpenAlex.

  1. [Application of computerized cognitive behavioral therapy in patients with persistent postural-perceptual dizziness].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Mental Health Education and Utilization Among Patients with Vestibular Disorders.Journal of clinical psychology in medical settings · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Stoyan PopkirovDepartment of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany. popkirov@gmail.com.
Jon StoneCentre for Clinical Brain Sciences, Western General Hospital, University of Edinburgh, Edinburgh, UK.
Dagny Holle-LeeDizziness and Vertigo Center Essen and Department of Neurology, University of Duisburg-Essen, Essen, Germany.
Ruhr University Bochum · DEUniversity of Duisburg-Essen · DEUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPersistent postural-perceptual dizziness (PPPD) is a newly defined disorder of functional dizziness that in the International Classification of Diseases in its 11th revision (ICD-11) supersedes phobic postural vertigo and chronic subjective dizziness. Despite efforts to unify the diagnosis of functional (somatoform) dizziness, patients will present with a variety of triggers, perpetuating factors, and comorbidities, requiring individualized treatment. This article will review different treatment strategies for this common functional neurological disorder and provide practical recommendations for tailored therapy. RECENT

findingsAn emerging understanding of the underlying pathophysiology that considers vestibular, postural, cognitive, and emotional aspects can enable patients to profit from vestibular rehabilitation, as well as cognitive-behavioral therapy (CBT). Crucially, approaches from CBT should inform and augment physiotherapeutic techniques, and, on the other hand, vestibular exercises or relaxation techniques can be integrated into CBT programs. Antidepressant medication might further facilitate rehabilitation, though the mechanisms are yet to be elucidated, and the level of evidence is low. In PPPD and related disorders, vestibular rehabilitation combined with CBT, and possibly supported by medication, can help patients escape a cycle of maladaptive balance control, recalibrate vestibular systems, and regain independence in everyday life.

Indexed as

Chronic subjective dizzinessCognitive-behavioral therapyFunctional neurological disorderPersistent postural-perceptual dizzinessPhobic postural vertigoVestibular rehabilitation

Identifiers

PMID30315375
OpenAlexW2897455123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.