ArticleEuropean journal of applied physiology2019
Physiological responses to hypoxic constant-load and high-intensity interval exercise sessions in healthy subjects.
Article in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Physiological Responses to High-Intensity Interval Exercise in Hypoxia Among Lean Males and Those With Overweight or Obesity.European journal of sport science · 2025Trial
- Trial
- Inter-effort hypoxia recovery during high-intensity intermittent exercise enhances oxygen uptake at the onset of efforts while maintaining exercise tolerance.European journal of applied physiology · 2026Article
- Muscle oxygen saturation plateau: Definition and verification in different oxygen availability conditions in locomotor and non-locomotor muscles.Experimental physiology · 2026Article
- Physiological and performance parameters associated with critical power decline in hypoxia among highly-trained endurance athletes.Biology of sport · 2026Article
- Moderate heart rate-matched hypoxic exercise: autonomic and cardiovascular responses to different degrees of hypoxic stress.European journal of applied physiology · 2026Article
- Critical power and critical oxygenation: examining transferability between normoxia and hypoxia.European journal of applied physiology · 2025Article
- Methods to match high-intensity interval exercise intensity in hypoxia and normoxia - A pilot study.Journal of exercise science and fitness · 2022Article
- Post-exercise cardiac autonomic and cardiovascular responses to heart rate-matched and work rate-matched hypoxic exercise.European journal of applied physiology · 2021Article
- Data Processing in Functional Near-Infrared Spectroscopy (fNIRS) Motor Control Research.Brain sciences · 2021Review
- The Effect of Breathing Patterns Common to Competitive Swimming on Gas Exchange and Muscle Deoxygenation During Heavy-Intensity Fartlek Exercise.Frontiers in physiology · 2021Article
- Muscle Oxygenation During Hypoxic Exercise in Children and Adults.Frontiers in physiology · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeThe aim of this study was to assess the acute cardiorespiratory as well as muscle and cerebral tissue oxygenation responses to submaximal constant-load (CL) and high-intensity interval (HII) cycling exercise performed in normoxia and in hypoxia at similar intensity, reproducing whole-body endurance exercise training sessions as performed in sedentary and clinical populations.
methodsHealthy subjects performed two CL (30 min, 75% of maximal heart rate, n = 12) and two HII (15 times 1-min high-intensity exercise-1-min passive recovery, n = 12) cycling exercise sessions in normoxia and in hypoxia [mean arterial oxygen saturation 76 ± 1% (clamped) during CL and 77 ± 5% (inspiratory oxygen fraction 0.135) during HII]. Cardiorespiratory and near-infrared spectroscopy parameters as well as the rate of perceived exertion were continuously recorded.
resultsPower output was 21 ± 11% and 15% (according to protocol design) lower in hypoxia compared to normoxia during CL and HII exercise sessions, respectively. Heart rate did not differ between normoxic and hypoxic exercise sessions, while minute ventilation was higher in hypoxia during HII exercise only (+ 13 ± 29%, p < 0.05). Quadriceps tissue saturation index did not differ significantly between normoxia and hypoxia (CL 60 ± 8% versus 59 ± 5%; HII 59 ± 10% versus 56 ± 9%; p > 0.05), while prefrontal cortex deoxygenation was significantly greater in hypoxia during both CL (66 ± 4% versus 56 ± 6%) and HII (58 ± 5% versus 55 ± 5%; p < 0.05) sessions. The rate of perceived exertion did not differ between normoxic and hypoxic CL (2.4 ± 1.7 versus 2.9 ± 1.8) and HII (6.9 ± 1.4 versus 7.5 ± 0.8) sessions (p > 0.05).
conclusionThis study indicates that at identical heart rate, reducing arterial oxygen saturation near 75% does not accentuate muscle deoxygenation during both CL and HII exercise sessions compared to normoxia. Hence, within these conditions, larger muscle hypoxic stress should not be expected.
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