Evidence map›Paper›PMID 30315241›Full record

ArticleMucosal immunology2019

Characterization of CD28

David M Habiel, Milena S Espindola, Chris Kitson, Anthony V Azzara, Ana Lucia Coelho, Barry Stripp, Cory M Hogaboam

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Review
  3. CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Senotherapy for chronic lung disease.Pharmacological reviews · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Risk factors and management of lung cancer in idiopathic pulmonary fibrosis: A comprehensive review.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  12. CD4Frontiers in immunology · 2025
    Review
  13. Article
  14. Immunobiology of pulmonary fibrosis.Frontiers in immunology · 2025
    Review
  15. PD-L1: From cancer immunotherapy to therapeutic implications in multiple disorders.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David M HabielDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. David.Habiel@gmail.com.
Milena S EspindolaDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Chris KitsonBristol-Myers Squibb, Fibrosis Discovery Biology, Pennington, NJ, 08534, USA.
Anthony V AzzaraBristol-Myers Squibb, Fibrosis Discovery Biology, Pennington, NJ, 08534, USA.
Ana Lucia CoelhoDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Barry StrippDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Cory M HogaboamDepartment of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. Cory.Hogaboam@cshs.org.
Cedars-Sinai Medical Center · USBristol-Myers Squibb (United States) · USLung Institute · US

Funding

Lung Immunopathology Training Stipend SupplementT32HL007517 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUKACS, NICHOLAS W · 1985 to 2022
$6.1M
Innate DNA sensing in rapidly progressing IPFR01HL123899 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI HOGABOAM, CORY M · 2015 to 2018
$2.0M
NHLBI NIH HHS R01 HL123899
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease, with unknown etiopathogenesis and suboptimal therapeutic options. Previous reports have shown that increased T-cell numbers and CD28

Indexed as

Airway RemodelingAnimalsAntibodies, MonoclonalCD28 AntigensCD8-Positive T-LymphocytesCells, CulturedCell SeparationCTLA-4 AntigenFlow CytometryHumansIdiopathic Pulmonary FibrosisImmunophenotypingLungMiceMice, SCIDProgrammed Cell Death 1 ReceptorAntibodies, MonoclonalCD28 AntigensCTLA-4 AntigenCtla4 protein, mousePdcd1 protein, mouseProgrammed Cell Death 1 Receptor

Identifiers

PMID30315241
PMCPMC6301115
OpenAlexW2896332308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.