ArticleScientific reports2018
Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- The basal level of salicylic acid represses the PRT6 N-degron pathway to modulate root growth and stress response in rice.Plant communications · 2025Article
- Translating weighted probabilistic bits to synthetic genetic circuits.The plant genome · 2025Article
- BIG enhances Arg/N-degron pathway-mediated protein degradation to regulate Arabidopsis hypoxia responses and suberin deposition.The Plant cell · 2024Article
- Label-Free Quantitative Proteomics Reveal the Involvement of PRT6 inInternational journal of molecular sciences · 2022Article
- Protein Tyrosine Nitration in Plant Nitric Oxide Signaling.Frontiers in plant science · 2022Review
- Multi-Omics Approaches Unravel Specific Features of Embryo and Endosperm in Rice Seed Germination.Frontiers in plant science · 2022Article
- Understanding a Mechanistic Basis of ABA Involvement in Plant Adaptation to Soil Flooding: The Current Standing.Plants (Basel, Switzerland) · 2021Review
- Comparative transcriptome analysis reveals function of TERF1 in promoting seed germination.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Nitric oxide function during oxygen deprivation in physiological and stress processes.Journal of experimental botany · 2021Review
- The PRT6 N-degron pathway restricts VERNALIZATION 2 to endogenous hypoxic niches to modulate plant development.The New phytologist · 2021Article
- The Central Negative Regulator of Flooding Tolerance, the PROTEOLYSIS 6 Branch of the N-degron Pathway, Adversely Modulates Salinity Tolerance inPlants (Basel, Switzerland) · 2020Article
- Conserved and Opposite Transcriptome Patterns during Germination inInternational journal of molecular sciences · 2020Article
- Identification and characterization of a female gametophyte defect inPlant signaling & behavior · 2020Article
- A simple and efficientPlant direct · 2020Article
- ThePlant direct · 2019Article
- Nitric oxide molecular targets: reprogramming plant development upon stress.Journal of experimental botany · 2019Review
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Authors and funding
8 authors at 3 institutions in 1 country.
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Abstract
The Arg/N-end rule pathway of ubiquitin-mediated proteolysis has multiple functions throughout plant development, notably in the transition from dormant seed to photoautotrophic seedling. PROTEOLYSIS6 (PRT6), an N-recognin E3 ligase of the Arg/N-end rule regulates the degradation of transcription factor substrates belonging to Group VII of the Ethylene Response Factor superfamily (ERFVIIs). It is not known whether ERFVIIs are associated with all known functions of the Arg/N-end rule, and the downstream pathways influenced by ERFVIIs are not fully defined. Here, we examined the relationship between PRT6 function, ERFVIIs and ABA signalling in Arabidopsis seedling establishment. Physiological analysis of seedlings revealed that N-end rule-regulated stabilisation of three of the five ERFVIIs, RAP2.12, RAP2.2 and RAP2.3, controls sugar sensitivity of seedling establishment and oil body breakdown following germination. ABA signalling components ABA INSENSITIVE (ABI)4 as well as ABI3 and ABI5 were found to enhance ABA sensitivity of germination and sugar sensitivity of establishment in a background containing stabilised ERFVIIs. However, N-end rule regulation of oil bodies was not dependent on canonical ABA signalling. We propose that the N-end rule serves to control multiple aspects of the seed to seedling transition by regulation of ERFVII activity, involving both ABA-dependent and independent signalling pathways.
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