Evidence map›Paper›PMID 30315197›Full record

ArticleNature communications2018

DUSP10 constrains innate IL-33-mediated cytokine production in ST2

Takeshi Yamamoto, Yusuke Endo, Atsushi Onodera, Kiyoshi Hirahara, Hikari K Asou, Takahiro Nakajima, Toshio Kanno, Yasuo Ouchi, Satoshi Uematsu, Hiroshi Nishimasu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
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  17. Optimal human pathogenic TThe Journal of allergy and clinical immunology · 2021
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Takeshi YamamotoDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Yusuke EndoDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Atsushi OnoderaDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Kiyoshi HiraharaDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Hikari K AsouDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Takahiro NakajimaDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Toshio KannoDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Yasuo OuchiDepartment of Mucosal Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Satoshi UematsuDepartment of Mucosal Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Hiroshi NishimasuDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo, Tokyo, 113-0032, Japan.
Osamu NurekiDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo, Tokyo, 113-0032, Japan.ORCID http://orcid.org/0000-0003-1813-7008
Damon J TumesCentre for Cancer Biology, University of South Australia and SA Pathology, cnr North Terrace & Morphett St bridge, GPO Box 2471, Adelaide, SA, 5001, Australia.ORCID http://orcid.org/0000-0001-5709-857X
Naoki ShimojoDepartment of Pediatrics, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan.
Toshinori NakayamaDepartment of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba, 260-8670, Japan. tnakayama@faculty.chiba-u.jp.
Chiba University · JPThe University of Tokyo · JPSouth Australia Pathology · AU

Funding

Ministry of Education, Culture, Sports, Science, and Technology (MEXT) 16H06224Ministry of Education, Culture, Sports, Science, and Technology (MEXT) 18H04665Ministry of Education, Culture, Sports, Science, and Technology (MEXT) 24790461Ministry of Education, Culture, Sports, Science, and Technology (MEXT) #26221305
6 · The paper itself

Abstract

ST2

Indexed as

AnimalsAnimals, Genetically ModifiedChromatin ImmunoprecipitationCytokinesDual-Specificity PhosphatasesEnzyme-Linked Immunosorbent AssayFlow CytometryGATA3 Transcription FactorHumansImmunoblottingInterleukin-33LymphocytesMiceMice, Inbred BALB Cp38 Mitogen-Activated Protein KinasesReal-Time Polymerase Chain ReactionCytokinesDual-Specificity PhosphatasesDusp10 protein, mouseGATA3 Transcription FactorInterleukin-33p38 Mitogen-Activated Protein Kinases

Identifiers

PMID30315197
PMCPMC6185962
OpenAlexW2897698729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.