ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
A Spinal Mechanism Related to Left-Right Symmetry Reduces Cutaneous Reflex Modulation Independently of Speed During Split-Belt Locomotion.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Changes in intra- and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats.The Journal of physiology · 2024Article
- Sensory feedback and central neuronal interactions in mouse locomotion.Royal Society open science · 2024Article
- Forelimb movements contribute to hindlimb cutaneous reflexes during locomotion in cats.Journal of neurophysiology · 2024Article
- Changes in intra- and interlimb reflexes from hindlimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats.The Journal of physiology · 2024Article
- Changes in intra- and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats.bioRxiv : the preprint server for biology · 2024Article
- Sensory Feedback and Central Neuronal Interactions in Mouse Locomotion.bioRxiv : the preprint server for biology · 2023Article
- Neuromechanical Strategies for Obstacle Negotiation during Overground Locomotion following Incomplete Spinal Cord Injury in Adult Cats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- A sensory signal related to left-right symmetry modulates intra- and interlimb cutaneous reflexes during locomotion in intact cats.Frontiers in systems neuroscience · 2023Article
- Modulation of the gait pattern during split-belt locomotion after lateral spinal cord hemisection in adult cats.Journal of neurophysiology · 2022Article
- Left-Right Locomotor Coordination in Human Neonates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- How Does the Central Nervous System for Posture and Locomotion Cope With Damage-Induced Neural Asymmetry?Frontiers in systems neuroscience · 2022Review
- State- and Condition-Dependent Modulation of the Hindlimb Locomotor Pattern in Intact and Spinal Cats Across Speeds.Frontiers in systems neuroscience · 2022Article
- Control of Mammalian Locomotion by Somatosensory Feedback.Comprehensive Physiology · 2021Article
- Relative Contribution of Proprioceptive and Vestibular Sensory Systems to Locomotion: Opportunities for Discovery in the Age of Molecular Science.International journal of molecular sciences · 2021Review
- Inhibition and Facilitation of the Spinal Locomotor Central Pattern Generator and Reflex Circuits by Somatosensory Feedback From the Lumbar and Perineal Regions After Spinal Cord Injury.Frontiers in neuroscience · 2021Review
- On the Organization of the Locomotor CPG: Insights From Split-Belt Locomotion and Mathematical Modeling.Frontiers in neuroscience · 2020Article
- The recovery of standing and locomotion after spinal cord injury does not require task-specific training.eLife · 2019Article
- Cutaneous sensory feedback from paw pads affects lateral balance control during split-belt locomotion in the cat.The Journal of experimental biology · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Task- and phase-dependent reflex modulation during locomotion is well established, but we do not know the signals driving this modulation. To determine whether signals related to left-right symmetry of the locomotor pattern modulate cutaneous reflexes, we stimulated the superficial peroneal nerve in five intact female cats and in four spinal-transected cats (spinal cats, two males and two females) during split-belt locomotion at different left-right speeds. We compared cutaneous reflexes evoked in three ipsilateral and two contralateral hindlimb muscles during split-belt locomotion with those evoked during tied-belt (equal left-right speeds) locomotion at matched speeds of the slow and fast limbs. Our results showed similar phase-dependent modulation of cutaneous reflexes during tied-belt and split-belt locomotion in intact and spinal cats. During tied-belt locomotion in intact cats, an increase in speed significantly increased reflex modulation from minimum to maximum values, whereas in spinal cats, we observed a significant decrease. However, in all muscles of intact and spinal cats, split-belt locomotion significantly reduced reflex modulation compared with tied-belt locomotion independently of which limb was stepping on the slow or fast belt. Additionally, reflex modulation correlated more with spatial left-right symmetry, as opposed to a temporal one, in intact and spinal cats. Our results indicate that signals related to left-right symmetry reduce cutaneous reflex modulation independently of speed via a spinal mechanism. We propose that asymmetric sensory feedback from the left and right legs alters the state of the spinal network, thereby reducing cutaneous reflexes to prevent inputs from destabilizing a potentially unstable pattern.
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