Evidence map›Paper›PMID 30315127›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Inhibitory Signaling to Ion Channels in Hippocampal Neurons Is Differentially Regulated by Alternative Macromolecular Complexes of RGS7.

Olga I Ostrovskaya, Cesare Orlandi, Ana Fajardo-Serrano, Samuel M Young, Rafael Lujan, Kirill A Martemyanov

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Developmental regulation of GABAHistology and histopathology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  10. Review
  11. Article
  12. Mechanisms and Regulation of Neuronal GABACurrent topics in behavioral neurosciences · 2022
    Review
  13. Article
  14. GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Review
  16. Frontiers in cellular neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Olga I OstrovskayaDepartment of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458.
Cesare OrlandiDepartment of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458.ORCID 0000-0002-4992-9350
Ana Fajardo-SerranoDepartamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, 02006 Albacete, Spain, and.ORCID 0000-0003-0645-8808
Samuel M YoungDepartments of Anatomy and Cell Biology and Department of Otolaryngology, Iowa Neuroscience Institute, and Aging Mind Brain Initiative, University of Iowa, Iowa City, Iowa 52242.
Rafael LujanDepartamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, 02006 Albacete, Spain, and.
Kirill A MartemyanovDepartment of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, kirill@scripps.edu.ORCID 0000-0002-9925-7599
Scripps Research Institute · USUniversity of Castilla-La Mancha · ESUniversity of Iowa · US

Funding

Orphan Receptors in Regulation of Neuronal G Protein SignalingR01MH105482 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Kirill A. Martemyanov · 2015 to 2026
$6.1M
Regulation of Synaptic Vesicle Dynamics in the Auditory SystemR01DC014093 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOUNG, SAMUEL MATTHEW · 2015 to 2024
$3.7M
Molecular Basis of RGS Protein Function in the StriatumR01DA021743 · NIDA · UNIVERSITY OF MINNESOTA · PI MARTEMYANOV, KIRILL A. · 2007 to 2011
$1.3M
Molecular Basis of RGS Protein Function in the StriatumK02DA026405 · NIDA · UNIVERSITY OF MINNESOTA · PI MARTEMYANOV, KIRILL A. · 2009 to 2019
$1.2M
NIDA NIH HHS K02 DA026405NIDA NIH HHS R01 DA021743NIDCD NIH HHS R01 DC014093NIMH NIH HHS R01 MH105482
6 · The paper itself

Abstract

The neuromodulatory effects of GABA on pyramidal neurons are mediated by GABA

Indexed as

AnimalsCaveolin 2Cells, CulturedFemaleG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHippocampusInsectaIon ChannelsMaleMiceMice, KnockoutNeural InhibitionNeuronsRGS ProteinsSignal TransductionCav2 protein, mouseCaveolin 2G Protein-Coupled Inwardly-Rectifying Potassium ChannelsIon ChannelsRgs7 protein, mouseRGS ProteinsGABABGPCRhippocampusion channelsneuromodulationRGS

Identifiers

PMID30315127
PMCPMC6234300
OpenAlexW2897060929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.