Evidence map›Paper›PMID 30314994›Full record

ArticleBioscience reports2019

MiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial-mesenchymal transitions of human glioma cells.

Zhixiao Li, Rongjun Qian, Jiadong Zhang, Xiwen Shi

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

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  19. The potential oncogenic role of the RAS-like GTP-binding gene RIT1 in glioblastoma.Cancer biomarkers : section A of Disease markers · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhixiao LiDepartment of Neurosurgery, The People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, People's Republic of China.
Rongjun QianDepartment of Neurosurgery, The People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, People's Republic of China rongjunqian168@126.com.
Jiadong ZhangDepartment of Neurosurgery, The People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, People's Republic of China.
Xiwen ShiDepartment of Neurosurgery, The People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, People's Republic of China.
Zhengzhou University · CNZhengzhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is a main subtype of high-grade gliomas with features in progressive brain tumor. Lipoma HMGIC fusion partner-like 3 (LHFPL3) is reported to be highly expressed in malignant glioma, but the relationship and mechanism between LHFPL3 and tumor is inexplicit. The present study aimed to screen the miRNAs targeting LHFPL3 and verify the pathogenesis and development of gliomas. Bioinformatics software predicted that miR-218-5p and miR-138-5p can specifically bind to

Indexed as

Gene Expression Regulation, NeoplasticApoptosisBrain NeoplasmsCell Cycle CheckpointsCell Line, TumorCell ProliferationComputational BiologyEpithelial-Mesenchymal TransitionGliomaHumansMembrane ProteinsMicroRNAsLHFPL3 protein, humanMembrane ProteinsMicroRNAsMIRN138 microRNA, humanMIRN218 microRNA, humanEMTglioblastomahas-miR-218-5pLipoma HMGIC fusion partner-like 3

Identifiers

PMID30314994
PMCPMC6395304
OpenAlexW2896000999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.