Evidence map›Paper›PMID 30314908›Full record

ArticleVaccine2019

Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017-2018.

Anyie J Li, Nandini Sreenivasan, Umme Ruman Siddiqi, Sanya Tahmina, Kinley Penjor, Ly Sovann, Amila Gunesekera, Jesse D Blanton, Lea Knopf, Terri B Hyde

Abstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
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  6. Review
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  12. A shorter post-exposure prophylaxis regimen for rabies, Pakistan.Bulletin of the World Health Organization · 2021
    Article
  13. Article
  14. Rabies control in South Asia requires a One Health approach.One health (Amsterdam, Netherlands) · 2021
    Article
  15. Article
  16. Human rabies: prospects for elimination.CAB reviews : perspectives in agriculture, veterinary science, nutrition and natural resources · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anyie J LiPHI/CDC Global Health Fellowship and ASPPH/CDC Allan Rosenfield Global Health Fellowship, Atlanta, USA. Electronic address: yrw5@cdc.gov.
Nandini SreenivasanCenters for Disease Control and Prevention, Atlanta, USA.
Umme Ruman SiddiqiDisease Control Unit, Communicable Disease Control, Directorate General of Health Services, Dhaka, Bangladesh.
Sanya TahminaDisease Control Unit, Communicable Disease Control, Directorate General of Health Services, Dhaka, Bangladesh.
Kinley PenjorDewathang Military Hospital, Department of Medical Services, Ministry of Health, Thimphu, Bhutan.
Ly SovannCommunicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia.
Amila GunesekeraMinistry of Health, Colombo, Sri Lanka.
Jesse D BlantonCenters for Disease Control and Prevention, Atlanta, USA.
Lea KnopfWorld Health Organization, Geneva, Switzerland.
Terri B HydeCenters for Disease Control and Prevention, Atlanta, USA.

Funding

CDC HHS NU2GGH002093Intramural CDC HHS CC999999OSELS CDC HHS U36 OE000002World Health Organization 001
6 · The paper itself

Abstract

backgroundThere are approximately 35,000 human deaths from rabies in Asia annually. Rabies can be prevented through timely post-exposure prophylaxis (PEP) consisting of wound washing, rabies vaccine, and in some cases, rabies immunoglobulin (RIG). However, access to rabies PEP often remains limited to urban areas and is cost-prohibitive. There is little information on procurement, distribution, monitoring, and reporting of rabies PEP.

methodsWe interviewed key informants in the public sector from various levels in Bangladesh, Bhutan, Cambodia, and Sri Lanka between March 2017 and May 2018 using a descriptive assessment tool to obtain information on procurement, distribution, monitoring, and reporting of rabies PEP. These four countries in Asia were chosen to showcase a range of rabies PEP systems. National rabies focal points were interviewed in each country and focal points helped identify additional key informants at lower levels.

resultsA total of 22 key informants were interviewed at various levels (central level to health facility level) including national rabies focal points in each country. Each country has a unique system for managing rabies PEP procurement, distribution, monitoring, and reporting. There are varying levels of PEP access for those with potential rabies exposures. Rabies PEP is available in select health facilities throughout the country in Bangladesh, Bhutan, and Sri Lanka. In Cambodia, rabies PEP is limited to two urban centers. The availability of RIG in all four countries is limited. In these four countries, most aspects of the rabies PEP distribution system operate independently of systems for other vaccines. However, in Bhutan, rabies PEP and Expanded Programme on Immunization (EPI) vaccines share cold chain space in some locations at the lowest level. All countries have a monitoring system in place, but there is limited reporting of data, particularly to the central level.

conclusionSystems to procure, deliver, monitor, and report on rabies PEP are variable across countries. Sharing information on practices more widely among countries can help programs to increase access to this life-saving treatment.

Indexed as

Health Services AccessibilityBangladeshBhutanCambodiaHumansImmunologic FactorsInterviews as TopicPost-Exposure ProphylaxisPublic SectorRabiesRabies VaccinesSri LankaImmunologic FactorsRabies VaccinesHuman rabiesRabies post-exposure prophylaxisRabies vaccineRabies virus

Identifiers

PMID30314908
PMCPMC6702106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.