Evidence map›Paper›PMID 30314793›Full record

Trial reportPreventive veterinary medicine2018

The impact of anthelmintic drugs on weight gain of smallholder goats in subtropical regions.

Paul R Bessell, Neil D Sargison, Kichuki Mirende, Ranjit Dash, Sanjay Prasad, Lamyaa Al-Riyami, Neil Gammon, Kristin Stuke, Roy Woolley, Miftahul Barbaruah and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Preventive veterinary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Aqueous extracts ofFrontiers in veterinary science · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Paul R BessellEpi Interventions, 17 Bangholm Avenue, Edinburgh, EH5 3AS, UK. Electronic address: prbessell@gmail.com.
Neil D SargisonUniversity of Edinburgh, Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Roslin, Midlothian, EH25 9RG, UK.
Kichuki MirendeDepartment of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, P.O. Box, 3019, Morogoro, Tanzania.
Ranjit DashGir Odisha Foundation, Kadei, Badachana, Jajapur, Odisha, India.
Sanjay PrasadVet Helpline India Pvt Ltd. H.No 31/32 Milanpur (Near Masjid No.1), Chandmari, Guwahati, 781021, Assam, India.
Lamyaa Al-RiyamiGALVmed, Doherty Building, Pentlands Science Park, Bush Loan, Penicuik, Edinburgh, EH26 0PZ, UK.
Neil GammonGALVmed, Doherty Building, Pentlands Science Park, Bush Loan, Penicuik, Edinburgh, EH26 0PZ, UK.
Kristin StukeGALVmed, Galana Plaza, 4(th) Floor, Wing C, Suite B, Galana Road, Kilimani, Nairobi, Kenya.
Roy WoolleyGALVmed, Doherty Building, Pentlands Science Park, Bush Loan, Penicuik, Edinburgh, EH26 0PZ, UK.
Miftahul BarbaruahVet Helpline India Pvt Ltd. H.No 31/32 Milanpur (Near Masjid No.1), Chandmari, Guwahati, 781021, Assam, India.
Philemon WamburaDepartment of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, P.O. Box, 3019, Morogoro, Tanzania.
Global Alliance for Livestock Veterinary Medicines · GBHelpAge India · INSokoine University of Agriculture · TZCentre for Clinical Interventions · AUUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helminth infections are recognised as a major impediment to the productivity of goats in smallholder production systems. We used a multilevel framework to estimate the impact that administration of locally available anthelminthic drugs can have on the weight gains of goats in smallholder settings in India and Tanzania. We recruited 234 goats from 92 households from Odisha state in India and 253 goats from 15 households from Dodoma region in Tanzania. The goats were non-pregnant adult females, and from each household a minimum of two goats were recruited wherever possible. Each goat was randomly assigned to treatment with a locally available anthelminthic drug, or non-treatment. Each animal was tagged, weighed and had its body condition score (BCS) assessed. Animals were followed up after 28 and 56 days and re-weighed. To account for the local variations in exposure to helminths and for variations between households and herds, the data were analysed in a multilevel mixed model with herd in village as nested random effects. Over the 56 days of study, the non-treated goats in India had gained a mean of 30.64 g per day (a daily gain of 0.23% baseline body weight) and in Tanzania 66.01 g per day (0.33% baseline body weight). From the mixed model, the treated goats in India gained a mean of 25.22 g per day more than non-treated goats, this is significantly greater than the weight gain in non-treated goats (p < 0.001). In Tanzania treated goats gained a mean of 9.878 g per day more than non-treated goats, which is also significantly greater than non-treated goats (p = 0.007). Furthermore, in India and Tanzania, goats with a lighter weight at the baseline survey gained greater amounts of weight. In both studies the BCS of the treated goats improved by a greater amount than the non-treated goats. In this study we have demonstrated that in certain settings, the administration of anthelminthic drugs has a clear beneficial impact on goat weight.

Indexed as

Animal HusbandryAnimalsAnthelminticsFemaleGoatsIndiaTanzaniaWeight GainAnthelminticsAnthelminthicsBody condition scoreGoatsParasitologySmallholderWeight

Identifiers

PMID30314793
PMCPMC6193133
OpenAlexW2889343239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.