Evidence map›Paper›PMID 30314757›Full record

ArticleImmunity2018

CD8

Laura M Snell, Bethany L MacLeod, Jaclyn C Law, Ivan Osokine, Heidi J Elsaesser, Kebria Hezaveh, Russell J Dickson, Marc A Gavin, Cynthia J Guidos, Tracy L McGaha and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 123 citations in OpenAlex.

  1. Renaissance of antiviral CD8Nature reviews. Immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Regulators of CD8Nature reviews. Immunology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Autoimmune CD4Immunity · 2024
    Article
  20. Circulating memory T cells and TCF1Journal of pharmaceutical analysis · 2024
    Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Laura M SnellPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada.
Bethany L MacLeodPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada.
Jaclyn C LawPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada; Department of Immunology, University of Toronto, Toronto, ON, M5S 1A8 Canada.
Ivan OsokineDepartment of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095 USA.
Heidi J ElsaesserPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada.
Kebria HezavehPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada.
Russell J DicksonPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada.
Marc A GavinTranslational Research Program, Benaroya Research Institute, Seattle, WA, 98101 USA.
Cynthia J GuidosDepartment of Immunology, University of Toronto, Toronto, ON, M5S 1A8 Canada; Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, Toronto, ON, M5G 0A4 Canada.
Tracy L McGahaPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada; Department of Immunology, University of Toronto, Toronto, ON, M5S 1A8 Canada.
David G BrooksPrincess Margaret Cancer Center, University Health Network, Toronto, ON, M5G 2M9 Canada; Department of Immunology, University of Toronto, Toronto, ON, M5S 1A8 Canada. Electronic address: dbrooks@uhnresearch.ca.
Princess Margaret Cancer Centre · CAUniversity Health Network · CABenaroya Research InstituteHospital for Sick Children · CAUniversity of California, Los Angeles · USUniversity of Toronto · CA

Funding

Mechanisms of Viral PersistenceR01AI085043 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BROOKS, DAVID G · 2010 to 2023
$4.5M
CIHR FDN148386NIAID NIH HHS R01 AI085043
6 · The paper itself

Abstract

CD8

Indexed as

AnimalsAntigen-Presenting CellsCD8-Positive T-LymphocytesCell DifferentiationChronic DiseaseGene Expression ProfilingImmunityImmunologic MemoryImmunotherapyLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMice, Inbred C57BLProteomicsT Cell Transcription Factor 1T Cell Transcription Factor 1cancerCD4 T cell helpCD8(+) T cellschronic infectiondendritic cellsIL-21immunotherapyLCMVPDL1T cell exhaustiontumor immunology

Identifiers

PMID30314757
PMCPMC8060917
OpenAlexW2897635750

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.