Evidence map›Paper›PMID 30314654›Full record

ArticleBiophysical journal2018

Acoustic Compressibility of Caenorhabditis elegans.

Thierry Baasch, Peter Reichert, Stefan Lakämper, Nadia Vertti-Quintero, Gamuret Hack, Xavier Casadevall I Solvas, Andrew deMello, Rudiyanto Gunawan, Jürg Dual

Abstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Acoustic Microfluidics.Annual review of analytical chemistry (Palo Alto, Calif.) · 2020
    Review
  8. Article
  9. Acoustofluidic methods in cell analysis.Trends in analytical chemistry : TRAC · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thierry BaaschInstitute for Mechanical Systems, Department of Mechanical and Process Engineering, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Peter ReichertInstitute for Mechanical Systems, Department of Mechanical and Process Engineering, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland. Electronic address: reichert@imes.mavt.ethz.ch.
Stefan LakämperInstitute for Mechanical Systems, Department of Mechanical and Process Engineering, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Nadia Vertti-QuinteroInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Gamuret HackInstitute for Mechanical Systems, Department of Mechanical and Process Engineering, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Xavier Casadevall I SolvasInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Andrew deMelloInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.
Rudiyanto GunawanInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Jürg DualInstitute for Mechanical Systems, Department of Mechanical and Process Engineering, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

The acoustic compressibility of Caenorhabditis elegans is a necessary parameter for further understanding the underlying physics of acoustic manipulation techniques of this widely used model organism in biological sciences. In this work, numerical simulations were combined with experimental trajectory velocimetry of L1 C. elegans larvae to estimate the acoustic compressibility of C. elegans. A method based on bulk acoustic wave acoustophoresis was used for trajectory velocimetry experiments in a microfluidic channel. The model-based data analysis took into account the different sizes and shapes of L1 C. elegans larvae (255 ± 26 μm in length and 15 ± 2 μm in diameter). Moreover, the top and bottom walls of the microfluidic channel were considered in the hydrodynamic drag coefficient calculations, for both the C. elegans and the calibration particles. The hydrodynamic interaction between the specimen and the channel walls was further minimized by acoustically levitating the C. elegans and the particles to the middle of the measurement channel. Our data suggest an acoustic compressibility κ

Indexed as

Caenorhabditis elegansLab-On-A-Chip DevicesAcousticsAnimalsBiomechanical PhenomenaCompressive StrengthHydrodynamics

Identifiers

PMID30314654
PMCPMC6224677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.