Evidence map›Paper›PMID 30314564›Full record

ArticleMaturitas2018

Personal, reproductive, and familial characteristics associated with bilateral oophorectomy in premenopausal women: A population-based case-control study.

Walter A Rocca, Liliana Gazzuola Rocca, Carin Y Smith, Brandon R Grossardt, Stephanie S Faubion, Lynne T Shuster, Elizabeth A Stewart, Michelle M Mielke, Kejal Kantarci, Virginia M Miller

Open access · greenAbstract read
In one paragraph

Article in Maturitas, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Risk of de novo cancer after premenopausal bilateral oophorectomy.American journal of obstetrics and gynecology · 2022
    Article
  5. Premature or early bilateral oophorectomy: a 2021 update.Climacteric : the journal of the International Menopause Society · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Walter A RoccaDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States; Department of Neurology, Mayo Clinic, Rochester, MN, United States; Women's Health Research Center, Mayo Clinic, Rochester, MN, United States. Electronic address: rocca@mayo.edu.
Liliana Gazzuola RoccaDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
Carin Y SmithDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
Brandon R GrossardtDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
Stephanie S FaubionWomen's Health Research Center, Mayo Clinic, Rochester, MN, United States; Women's Health Clinic, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Lynne T ShusterWomen's Health Research Center, Mayo Clinic, Rochester, MN, United States; Women's Health Clinic, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Elizabeth A StewartWomen's Health Research Center, Mayo Clinic, Rochester, MN, United States; Department of Surgery, Mayo Clinic, Rochester, MN, United States; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, United States.
Michelle M MielkeDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States; Department of Neurology, Mayo Clinic, Rochester, MN, United States; Women's Health Research Center, Mayo Clinic, Rochester, MN, United States.
Kejal KantarciWomen's Health Research Center, Mayo Clinic, Rochester, MN, United States; Department of Radiology, Mayo Clinic, Rochester, MN, United States.
Virginia M MillerWomen's Health Research Center, Mayo Clinic, Rochester, MN, United States; Department of Surgery, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic in Arizona · USMayo Clinic · USMayo Clinic in Florida · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
SEX STEROIDS, GROWTH FACTORS, &BONE CELL FUNCTIONP01AG004875 · NIA · MAYO CLINIC ROCHESTER · PI MONROE, DAVID G · 1985 to 2019
$30.8M
Prevention of Alzheimer's disease in women: risks and benefits of hormone therapyRF1AG057547 · NIA · MAYO CLINIC ROCHESTER · PI GLEASON, CAREY E, KANTARCI, KEJAL · 2017 to 2020
$11.1M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Sex-specific Risk for Vascular Dysfunction and Cognitive DeclineP50AG044170 · NIA · MAYO CLINIC ROCHESTER · PI MILLER, VIRGINIA M · 2012 to 2017
$6.1M
Reproductive risk factors for Alzheimer's disease dementia and pathologyRF1AG055151 · NIA · MAYO CLINIC ROCHESTER · PI MIELKE, MICHELLE M, ROCCA, WALTER A · 2017 to 2017
$4.0M
Multiple Chronic Conditions and AgingR01AG052425 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2017 to 2021
$3.3M
Sphingolipids and Inflammation in the Development and Progression of Alzheimer'sR01AG049704 · NIA · MAYO CLINIC ROCHESTER · PI MIELKE, MICHELLE M · 2015 to 2018
$1.5M
NCATS NIH HHS UL1 TR002377NIA NIH HHS P01 AG004875NIA NIH HHS P50 AG044170NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG049704NIA NIH HHS R01 AG052425NIA NIH HHS RF1 AG055151NIA NIH HHS RF1 AG057547NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

objectivesWe investigated the association of personal, reproductive, and familial characteristics with bilateral oophorectomy performed for nonmalignant indications in a US population. STUDY

designIn an established cohort study, we used the records-linkage system of the Rochester Epidemiology Project (REP http://www.rochesterproject.org) to identify 1653 premenopausal women who underwent bilateral oophorectomy in Olmsted County, Minnesota between 1988 and 2007 for a nonmalignant indication. Each woman was matched by age (±1 year) to a population-based referent woman who had not undergone bilateral oophorectomy as of the index date. We used case-control analyses to investigate several characteristics associated with bilateral oophorectomy. Odds ratios and their 95% confidence intervals were adjusted for race, education, and income.

resultsIn the overall analyses, infertility was more common in women who underwent bilateral oophorectomy than in the controls, whereas use of oral contraceptives, a history of breast feeding, and fibrocystic breast disease were less common. The women who underwent bilateral oophorectomy weighed more than controls, had a higher body mass index and were younger at menarche. The associations were more pronounced for women who underwent the bilateral oophorectomy before age 46 years, and some associations were different for women with or without a benign ovarian indication. Reported family histories of uterine and other cancers were more common in women without a benign ovarian indication.

conclusionsWe identified a number of personal, reproductive, and familial characteristics that were associated with bilateral oophorectomy over a 20-year period. Our historical findings may help inform decision-making about oophorectomy in the future.

Indexed as

OvariectomyPremenopauseAdultBody Mass IndexBreast FeedingCase-Control StudiesFamily CharacteristicsFemaleFibrocystic Breast DiseaseHumansMedical History TakingMenarcheMiddle AgedMinnesotaOdds RatioReproductionBilateral oophorectomyBody mass indexFamily historyOral contraceptivesReproductive historySmoking

Identifiers

PMID30314564
PMCPMC6231412
OpenAlexW2891034920

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.