Evidence map›Paper›PMID 30314343›Full record

ReviewInternational journal of molecular sciences2018

Overview of the Maturation Machinery of the H-Cluster of [FeFe]-Hydrogenases with a Focus on HydF.

Marco Bortolus, Paola Costantini, Davide Doni, Donatella Carbonera

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. HydG, the "dangler" iron, and catalytic production of free CO and CNDalton transactions (Cambridge, England : 2003) · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. H-cluster assembly intermediates built on HydF by the radical SAM enzymes HydE and HydG.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2019
    Article
  8. The final steps of [FeFe]-hydrogenase maturation.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco BortolusDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy. marco.bortolus@unipd.it.ORCID 0000-0002-6033-6521
Paola CostantiniDepartment of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy. paola.costantini@unipd.it.
Davide DoniDepartment of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy. davide.doni.2@phd.unipd.it.
Donatella CarboneraDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy. donatella.carbonera@unipd.it.

Funding

Fondazione Cassa di Risparmio di Padova e Rovigo Bortolus Starting GrantFondazione Cassa di Risparmio di Padova e Rovigo M3PCUniversità degli Studi di Padova CPDA149178/14
6 · The paper itself

Abstract

Hydrogen production in nature is performed by hydrogenases. Among them, [FeFe]-hydrogenases have a peculiar active site, named H-cluster, that is made of two parts, synthesized in different pathways. The cubane sub-cluster requires the normal iron-sulfur cluster maturation machinery. The [2Fe] sub-cluster instead requires a dedicated set of maturase proteins, HydE, HydF, and HydG that work to assemble the cluster and deliver it to the apo-hydrogenase. In particular, the delivery is performed by HydF. In this review, we will perform an overview of the latest knowledge on the maturation machinery of the H-cluster, focusing in particular on HydF.

Indexed as

CatalysisHydrogenHydrogenaseIronModels, MolecularProtein BindingProtein Interaction Domains and MotifsStructure-Activity RelationshipHydrogenHydrogenaseIron[FeFe]-hydrogenasesHydEHydFHydGhydrogenasesmaturases

Identifiers

PMID30314343
PMCPMC6212873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.