Evidence map›Paper›PMID 30314324›Full record

ArticlePharmaceutics2018

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant

Ruba Malkawi, Abhishek Iyer, Anish Parmar, Daniel G Lloyd, Eunice Tze Leng Goh, Edward J Taylor, Sarir Sarmad, Annemieke Madder, Rajamani Lakshminarayanan, Ishwar Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruba MalkawiSchool of Pharmacy, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. 16657045@students.lincoln.ac.uk.
Abhishek IyerSchool of Pharmacy, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. Abhishek.Iyer@UGent.be.ORCID 0000-0002-5310-1302
Anish ParmarSchool of Pharmacy, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. aparmar@lincoln.ac.uk.
Daniel G LloydSchool of Life Sciences, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. dlloyd@lincoln.ac.uk.
Eunice Tze Leng GohSingapore Eye Research Institute, The Academia, Discovery Tower Level 6, 20 College Road, Singapore 169857, Singapore. eunice.goh.t.l@seri.com.sg.
Edward J TaylorSchool of Life Sciences, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. etaylor@lincoln.ac.uk.
Sarir SarmadSchool of Chemistry, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. SSarmad@lincoln.ac.uk.
Annemieke MadderOrganic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 (S4), B-9000 Ghent, Belgium. annemieke.madder@ugent.be.ORCID 0000-0003-0179-7608
Rajamani LakshminarayananSingapore Eye Research Institute, The Academia, Discovery Tower Level 6, 20 College Road, Singapore 169857, Singapore. lakshminarayanan.rajamani@seri.com.sg.ORCID 0000-0001-8214-5315
Ishwar SinghSchool of Pharmacy, Joseph Banks Laboratories, University of Lincoln, Green Lane, Lincoln LN6 7DL, UK. isingh@lincoln.ac.uk.ORCID 0000-0001-7822-1063

Funding

Rosetrees Trust JS16/M583
6 · The paper itself

Abstract

Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant

Indexed as

disulfide bridgeMRSAteixobactin

Identifiers

PMID30314324
PMCPMC6321233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.