Evidence map›Paper›PMID 30314286›Full record

ArticleJournal of clinical medicine2018

PLP1 Mutations in Patients with Multiple Sclerosis: Identification of a New Mutation and Potential Pathogenicity of the Mutations.

Nancy C Cloake, Jun Yan, Atefeh Aminian, Michael P Pender, Judith M Greer

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. PLP1 gene mutations cause spastic paraplegia type 2 in three families.Annals of clinical and translational neurology · 2023
    Article
  7. Article
  8. Human myelin proteolipid protein structure and lipid bilayer stacking.Cellular and molecular life sciences : CMLS · 2022
    Article
  9. Article
  10. Hereditary Spastic Paraplegia: An Update.International journal of molecular sciences · 2022
    Review
  11. Review
  12. TemporalACS omega · 2020
    Article
  13. Review
  14. SeXX Matters in Multiple Sclerosis.Frontiers in neurology · 2020
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nancy C CloakeUQ Centre for Clinical Research, the University of Queensland, Brisbane, QLD 4029, Australia. Nancy.Cloake@qimrberghofer.edu.au.
Jun YanUQ Centre for Clinical Research, the University of Queensland, Brisbane, QLD 4029, Australia. j.yan@uq.edu.au.
Atefeh AminianUQ Centre for Clinical Research, the University of Queensland, Brisbane, QLD 4029, Australia. atefeh.aminian@yahoo.com.
Michael P PenderFaculty of Medicine, the University of Queensland, Brisbane, QLD 4029, Australia. m.pender@uq.edu.au.
Judith M GreerUQ Centre for Clinical Research, the University of Queensland, Brisbane, QLD 4029, Australia. j.greer@uq.edu.au.ORCID 0000-0003-4440-4309

Funding

Multiple Sclerosis Research Australia 10053
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epitopesmultiple sclerosis (MS)myelin proteolipid protein (PLP)point mutationsprimary progressive MSunfolded protein responsewomen

Identifiers

PMID30314286
PMCPMC6210135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.