ArticleNeuroImage. Clinical2018
Lesion locations associated with persistent proprioceptive impairment in the upper limbs after stroke.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Psychometric properties of technology-assisted matching paradigms in post-stroke upper limb proprioceptive assessment: a scoping review.Frontiers in neurology · 2025Pooled it
- Correlation Between Proprioceptive Impairment and Motor Deficits After Stroke: A Meta-Analysis Review.Frontiers in neurology · 2021Pooled it
- Utility and User Experience with 3-Dimensional Vibrotactile Kinesthetic Feedback for Improving Reach-to-Grasp Accuracy and Efficiency After Stroke: A Case Series.Restorative neurology and neuroscience · 2026Trial
- Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients.Stroke and vascular neurology · 2022Trial
- Attenuated sensorimotor hemodynamic responses and altered cortical dynamics during passive proprioceptive-related stimulation after stroke: a multidimensional fNIRS study.Frontiers in neurology · 2026Article
- FRONTAL AND PARIETAL CONTRIBUTIONS TO PROPRIOCEPTION AND MOTOR SKILL LEARNING.bioRxiv : the preprint server for biology · 2025Article
- Movement Impairments May Not Preclude Visuomotor Adaptation After Stroke.Brain sciences · 2025Article
- The Role of Sensory Impairments on Recovery and Rehabilitation After Stroke.Current neurology and neuroscience reports · 2025Review
- The impact of proprioception impairment on gait function in stroke survivors: a comprehensive review.Frontiers in neurology · 2025Review
- The correlation between lower limb spasticity and proprioceptive dysfunction in post-stroke patients.Frontiers in neurology · 2025Article
- Robot-aided assessment and associated brain lesions of impaired ankle proprioception in chronic stroke.Journal of neuroengineering and rehabilitation · 2024Article
- The independence of impairments in proprioception and visuomotor adaptation after stroke.Journal of neuroengineering and rehabilitation · 2024Article
- The causal relationship between human brain morphometry and knee osteoarthritis: a two-sample Mendelian randomization study.Frontiers in genetics · 2024Article
- Resting state functional connectivity associated with impaired proprioception post-stroke.Human brain mapping · 2024Article
- Article
- Observational
- The impact of lesion side on bilateral upper limb coordination after stroke.Journal of neuroengineering and rehabilitation · 2023Article
- A robot-based interception task to quantify upper limb impairments in proprioceptive and visual feedback after stroke.Journal of neuroengineering and rehabilitation · 2023Article
- Article
- Clinical, Neuroimaging and Robotic Measures Predict Long-Term Proprioceptive Impairments following Stroke.Brain sciences · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proprioceptive deficits are common after stroke and have been associated with poorer recovery. Relatively little is known about the brain regions beyond primary somatosensory cortex that contribute to the percept of proprioception in humans. We examined a large sample (n = 153) of stroke survivors longitudinally to determine which brain regions were associated with persistent post-stroke proprioceptive deficits. A robotic exoskeleton quantified two components of proprioception, position sense and kinesthesia (movement sense), at 2 weeks and again at 6 months post-stroke. A statistical region of interest (sROI) analysis compared the lesion-behaviour relationships of those subjects with cortical and subcortical stroke (n = 136). The impact of damage to brainstem and cerebellum (n = 17) was examined separately. Results indicate that damage to the supramarginal gyrus, the arcuate fasciculus, and Heschl's gyrus are associated with deficits in position sense and kinesthesia at 6 months post-stroke. These results suggest that regions beyond the primary somatosensory cortex contribute to our sense of limb position and movement. This information extends our understanding of proprioceptive processing and may inform personalized interventions such as non-invasive brain stimulation where specific brain regions can be targeted to potentially improve stroke recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.