Evidence map›Paper›PMID 30312601›Full record

ArticleJournal of immunological methods2018

Sequencing the peripheral blood B and T cell repertoire - Quantifying robustness and limitations.

Joel S Simon, Sergio Botero, Sanford M Simon

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunological methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joel S SimonLaboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, United States.
Sergio BoteroLaboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, United States.
Sanford M SimonLaboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, United States. Electronic address: simon@rockefeller.edu.

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Project 4: ImmunovirotherapyP50CA210964 · NCI · MAYO CLINIC ROCHESTER · PI Rory Smoot · 2018 to 2026
$20.5M
Cellular Pathogenesis of Fibrolamellar Hepatocellular CarcinomaR56CA207929 · NCI · ROCKEFELLER UNIVERSITY · PI SIMON, SANFORD M · 2016 to 2017
$593k
NCI NIH HHS P30 CA015083NCI NIH HHS P50 CA210964NCI NIH HHS R56 CA207929
6 · The paper itself

Abstract

The adaptive immune response generates a large repertoire of T cells with T-cell receptors (TCR

Indexed as

Sequence Analysis, DNAB-LymphocytesComplementarity Determining RegionsFemaleHumansImmunoglobulin GImmunoglobulin Heavy ChainsMaleReceptors, Antigen, B-CellReceptors, Antigen, T-Cell, alpha-betaT-LymphocytesComplementarity Determining RegionsImmunoglobulin GImmunoglobulin Heavy ChainsReceptors, Antigen, B-CellReceptors, Antigen, T-Cell, alpha-betaB cell receptorCancerImmune repertoireT cell receptor

Identifiers

PMID30312601
PMCPMC6355145

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.