ArticleJournal of experimental botany2018
Arabidopsis UMAMIT24 and 25 are amino acid exporters involved in seed loading.
Article in Journal of experimental botany, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 65 citations in OpenAlex.
- Genome-Wide Identification of the Soybean UMAMIT Family and Functional Analysis ofInternational journal of molecular sciences · 2026Article
- Symbiosis-associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula.The New phytologist · 2026Article
- Genome-wide identification of the UMAMIT gene family in Medicago sativa L. and analysis of the response of umamits mutant to abiotic stress.BMC plant biology · 2026Article
- The Arabidopsis neutral amino acid transporter UmamiT20 confers Botrytis cinerea susceptibility.Journal of experimental botany · 2026Article
- Regulation of grain protein content by the amino acid permease gene OsAAP4 in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- The Arabidopsis UMAMIT30 transporter contributes to amino acid root exudation.BMC plant biology · 2026Article
- Metabolic engineering of soybean for improving grain quality for animal consumption.Frontiers in plant science · 2026Review
- Metabolic flux analysis to increase oil in seeds.Plant physiology · 2025Review
- Article
- New insights into the evolution and function of the UMAMIT (USUALLY MULTIPLE ACIDS MOVE IN AND OUT TRANSPORTER) gene family.Journal of plant research · 2025Article
- Article
- Bioinformatics and Expression Analyses of theInternational journal of molecular sciences · 2024Article
- Impact of whole-genome duplications on structural variant evolution in Cochlearia.Nature communications · 2024Article
- UMAMIT44 is a key player in glutamate export from Arabidopsis chloroplasts.The Plant cell · 2024Article
- An UMAMIT-GTR transporter cascade controls glucosinolate seed loading in Arabidopsis.Nature plants · 2024Article
- Article
- Article
- Nutrient accumulation and transcriptome patterns during grain development in rice.Journal of experimental botany · 2023Article
- The putative transporter MtUMAMIT14 participates in nodule formation in Medicago truncatula.Scientific reports · 2023Article
- Identification of key amino acid residues in AtUMAMIT29 for transport of glucosinolates.Frontiers in plant science · 2023Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phloem-derived amino acids are the major source of nitrogen supplied to developing seeds. Amino acid transfer from the maternal to the filial tissue requires at least one cellular export step from the maternal tissue prior to the import into the symplasmically isolated embryo. Some members of UMAMIT (usually multiple acids move in an out transporter) family (UMAMIT11, 14, 18, 28, and 29) have previously been implicated in this process. Here we show that additional members of the UMAMIT family, UMAMIT24 and UMAMIT25, also function in amino acid transfer in developing seeds. Using a recently published yeast-based assay allowing detection of amino acid secretion, we showed that UMAMIT24 and UMAMIT25 promote export of a broad range of amino acids in yeast. In plants, UMAMIT24 and UMAMIT25 are expressed in distinct tissues within developing seeds; UMAMIT24 is mainly expressed in the chalazal seed coat and localized on the tonoplast, whereas the plasma membrane-localized UMAMIT25 is expressed in endosperm cells. Seed amino acid contents of umamit24 and umamit25 knockout lines were both decreased during embryogenesis compared with the wild type, but recovered in the mature seeds without any deleterious effect on yield. The results suggest that UMAMIT24 and 25 play different roles in amino acid translocation from the maternal to filial tissue; UMAMIT24 could have a role in temporary storage of amino acids in the chalaza, while UMAMIT25 would mediate amino acid export from the endosperm, the last step before amino acids are taken up by the developing embryo.
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