ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Declining Incident Dementia Rates Across Four Population-Based Birth Cohorts.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed.
- Trends in Dementia Incidence, Prevalence, and Mortality among Older Hong Kong Chinese, 2005-2019: A Population-Based Study.Neuroepidemiology · 2026Article
- Alzheimer Syndrome or Age-Related Dementia-History, Therapy and Prevention.Journal of clinical medicine · 2025Article
- Decline in Incidence and Prevalence of Dementia: An Analysis of Outpatient Claims Data.Deutsches Arzteblatt international · 2025Observational
- Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study.BMJ (Clinical research ed.) · 2025Article
- Changing Story of the Dementia Epidemic.JAMA · 2025Article
- Charting Alzheimer's Disease and Dementia: Epidemiological Insights, Risk Factors and Prevention Pathways.Journal of clinical medicine · 2024Review
- 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History.Journal of clinical medicine · 2024Review
- Time trends in Alzheimer's disease mortality attributable to metabolic risks and smoking in China from 1990 to 2019: an age-period-cohort analysis.Frontiers in aging neuroscience · 2024Article
- Outdoor nighttime light exposure (light pollution) is associated with Alzheimer's disease.Frontiers in neuroscience · 2024Article
- Dementia incidence trend in England and Wales, 2002-19, and projection for dementia burden to 2040: analysis of data from the English Longitudinal Study of Ageing.The Lancet. Public health · 2023Article
- Direct Effect of Life-Course Socioeconomic Status on Late-Life Cognition and Cognitive Decline in the Rush Memory and Aging Project.American journal of epidemiology · 2023Article
- Dementia and Related Comorbidities in the Population Aged 90 and Over in the Vitality 90+ Study, Finland: Patterns and Trends From 2001 to 2018.Journal of aging and health · 2023Article
- Decreasing Incidence and Prevalence of Dementia Among Octogenarians: A Population-Based Study on 3 Cohorts Born 30 Years Apart.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Secular trends in prevalent mild cognitive impairment: Data from the Swedish population-based study Good Aging in Skåne.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Ambient fine particulate matter exposure and incident mild cognitive impairment and dementia.Journal of the American Geriatrics Society · 2021Article
- Analysis of Time Trends in Alzheimer's Disease and Related Dementias Using Partitioning Approach.Journal of Alzheimer's disease : JAD · 2021Article
- What does (low) education mean in terms of dementia risk? A systematic review and meta-analysis highlighting inconsistency in measuring and operationalising education.SSM - population health · 2020Review
- Carotid Intima-Media Thickness and Markers of Brain Health in a Biracial Middle-Aged Cohort: CARDIA Brain MRI Sub-study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Depression Symptoms Declining Among Older Adults: Birth Cohort Analyses From the Rust Belt.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundIncidence rates of dementia appear to be declining in high-income countries according to several large epidemiological studies. We aimed to describe declining incident dementia rates across successive birth cohorts in a U.S. population-based sample and to explore the influences of sex and education on these trends.
methodsWe pooled data from two community-sampled prospective cohort studies with similar study aims and contiguous sampling regions: the Monongahela Valley Independent Elders Survey (1987-2001) and the Monongahela-Youghiogheny Healthy Aging Team (2006-Ongoing). We identified four decade-long birth cohorts spanning birth years 1902-1941. In an analysis sample of 3,010 participants (61% women, mean baseline age = 75.7 years, mean follow-up = 7.1 years), we identified 257 cases of incident dementia indicated by a Clinical Dementia Rating of 1.0 or higher. We used Poisson regression to model incident dementia rates by birth cohort, age, sex, education, and interactions of Sex × Cohort and Sex × Education. We further examined whether cohort effects varied by education, testing a Cohort × Education interaction and stratifying the models by education.
resultsCompared to the earliest birth cohort (1902-1911), each subsequent cohort had a significantly lower incident dementia rate (1912-1921: incidence rate ratio [IRR] = 0.655, 95% confidence interval [95% CI] = 0.477-0.899; 1922-1931: IRR = 0.387, 95% CI = 0.265-0.564; 1932-1941: IRR = 0.233, 95% CI = 0.121-0.449). We observed no significant interactions of either sex or education with birth cohort.
conclusionsA decline in incident dementia rates was observed across successive birth cohorts independent of sex, education, and age.
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