ArticlePloS one2018
A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Meta-QTLs, ortho-meta-QTLs and candidate genes for grain yield and associated traits in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Pooled it
- Meta-Analysis of the QTLome of Fusarium Head Blight Resistance in Bread Wheat: Refining the Current Puzzle.Frontiers in plant science · 2019Pooled it
- Deciphering the genetic basis of yield components in wheat by integrating hyperspectral-based phenomes.Plant phenomics (Washington, D.C.) · 2026Article
- Genetic dissection of cold stress tolerance and yield potential under cold stress in nested synthetic wheat (Triticum aestivum L.) introgression libraries using multi-locus genome-wide association and haplotype analysis.Functional & integrative genomics · 2026Article
- Comparative transcriptome analysis unravels genotype-specific defense strategies in anthracnose-resistant and susceptible litchi cultivars.Scientific reports · 2026Article
- Bulked Segregant Analysis Revealed the Common Resistant QTLs Associated with Fusarium Ear Rot and Gibberella Ear Rot in Maize.Plants (Basel, Switzerland) · 2026Article
- Unveiling the genetic architecture of stripe rust resistance in wheat: a region-specific GWAS in Xinjiang, China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- MAGIC population-based genetic dissection of yield-related traits under heat stress in wheat (Frontiers in plant science · 2026Article
- Markers Associated with Starch, Protein and Asparagine Content in Grain of Common Wheat.Genes · 2025Article
- A novel quantitative trait locus for barley yellow dwarf virus resistance and kernel traits on chromosome 2D of a wheat cultivar Jagger.The plant genome · 2025Article
- Chlorophyll Fluorescence in Wheat Breeding for Heat and Drought Tolerance.Plants (Basel, Switzerland) · 2024Review
- Molecular Investigations to Improve Fusarium Head Blight Resistance in Wheat: An Update Focusing on Multi-Omics Approaches.Plants (Basel, Switzerland) · 2024Review
- Genome-Wide Association Analysis of Yield-Related Traits and Candidate Genes in Vegetable Soybean.Plants (Basel, Switzerland) · 2024Article
- Trichothecenes and Fumonisins: Key Players inToxins · 2024Review
- Exploring the genetic architecture of powdery mildew resistance in wheat through QTL meta-analysis.Frontiers in plant science · 2024Article
- Occurrence of Mycotoxins in Foods: Unraveling the Knowledge Gaps on Their Persistence in Food Production Systems.Foods (Basel, Switzerland) · 2023Review
- Meta-QTL analysis in wheat: progress, challenges and opportunities.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
- Comparative transcriptomic analysis of wheat cultivars differing in their resistance to Fusarium head blight infection during grain-filling stages reveals unique defense mechanisms at play.BMC plant biology · 2023Article
- Deoxynivalenol accumulation and detoxification in cereals and its potential role in wheat-aBIOTECH · 2023Review
- Comprehensive meta-QTL analysis for dissecting the genetic architecture of stripe rust resistance in bread wheat.BMC genomics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mycotoxin deoxynivalenol (DON) serves as a plant disease virulence factor for the fungi Fusarium graminearum and F. culmorum during the development of Fusarium head blight (FHB) disease on wheat. A wheat cytochrome P450 gene from the subfamily CYP72A, TaCYP72A, was cloned from wheat cultivar CM82036. TaCYP72A was located on chromosome 3A with homeologs present on 3B and 3D of the wheat genome. Using gene expression studies, we showed that TaCYP72A variants were activated in wheat spikelets as an early response to F. graminearum, and this activation was in response to the mycotoxic Fusarium virulence factor deoxynivalenol (DON). Virus induced gene silencing (VIGS) studies in wheat heads revealed that this gene family contributes to DON resistance. VIGS resulted in more DON-induced discoloration of spikelets, as compared to mock VIGS treatment. In addition to positively affecting DON resistance, TaCYP72A also had a positive effect on grain number. VIGS of TaCYP72A genes reduced grain number by more than 59%. Thus, we provide evidence that TaCYP72A contributes to host resistance to DON and conclude that this gene family warrants further assessment as positive contributors to both biotic stress resistance and grain development in wheat.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.