Evidence map›Paper›PMID 30312343›Full record

ArticlePloS one2018

Sexual health of young people with perinatal HIV and HIV negative young people in England.

Ali Judd, Caroline Foster, Lindsay C Thompson, Kate Sturgeon, Marthe Le Prevost, Eva Jungmann, Katie Rowson, Hannah Castro, Diana M Gibb, Adolescents and Adults Living with Perinatal HIV (AALPHI) Steering Committee

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Peritransition Outcomes of Southeast Asian Adolescents and Young Adults With HIV Transferring From Pediatric to Adult Care.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali JuddMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.ORCID 0000-0003-3176-5295
Caroline FosterImperial College Healthcare NHS Trust, London, United Kingdom.
Lindsay C ThompsonMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Kate SturgeonMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Marthe Le PrevostMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Eva JungmannCentral and North West London NHS Foundation Trust, London, United Kingdom.
Katie RowsonMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Hannah CastroMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Diana M GibbMRC Clinical Trials Unit at UCL, University College London, London, United Kingdom.
Adolescents and Adults Living with Perinatal HIV (AALPHI) Steering Committee

Funding

Medical Research Council MC_UU_12023/17Medical Research Council MC_UU_12023/26
6 · The paper itself

Abstract

As adolescents with perinatal HIV (PHIV) survive into adulthood, gaining insight into sexual behaviour and risk-taking is important. Between 2013-2015, 296 PHIV aged 13-21 years and 96 HIV negative affected adolescents (13-23 years) were recruited to the Adolescents and Adults Living with Perinatal HIV (AALPHI) cohort in England. Sexual health data were collected through computer-assisted self-interview questionnaires. Quality of life and household deprivation were also measured. T-tests compared means, and χ2 proportions; logistic regression examined predictors of ever having sex. 120(41%) PHIV and 31(32%) HIV- young people were male, 254(86%) and 70(73%) were black, median age 16 [IQR 15,18] and 16 [14,18] years respectively. 77(26%) PHIV had a previous AIDS diagnosis. 93(32%) PHIV and 38(40%) HIV- had ever had sex; median number of partners was 3 [1,6] and 4 [1,6] respectively. 54 (41%) of 131 young people who were sexually active reported not always using condoms, including 32% (30/93) of PHIV. In multivariable analysis, older age, male sex, worse deprivation score, worse quality of life, and alcohol and/or drugs were associated with ever having sex, but not HIV status. 12/30 PHIV reporting unprotected sex had at least one HIV viral load ≥200c/ml in the previous 12 months. Age at first sex and number of sexual partners were similar among PHIV and HIV-, and comparable to normative data. In conclusion, small numbers of PHIV reported condomless sex with a detectable viral load, which could result in HIV transmission, indicating the need for targeted sexual health and ART adherence interventions for young people with perinatal HIV.

Indexed as

Sexual BehaviorSexual HealthAdolescentAdolescent BehaviorCondomsEnglandFemaleHealth Risk BehaviorsHIV InfectionsHumansMalePapillomavirus VaccinesRisk FactorsSubstance-Related DisordersViral LoadYoung AdultPapillomavirus Vaccines

Identifiers

PMID30312343
PMCPMC6185844

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.