ArticlePloS one2018
The association between major complications of immobility during hospitalization and quality of life among bedridden patients: A 3 month prospective multi-center study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
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- Brace yourself: routine postoperative bracing after adult spinal deformity surgery offers no clinical benefit and may increase harm.Journal of spine surgery (Hong Kong) · 2025Article
- Prescription Sequence Symmetry Analysis for Detection of Chronic Opioid Use Adverse Event Signals Using Administrative Claims Data.Pharmacotherapy · 2025Article
- In-Hospital Mortality Among 40,253 Older Adults with Hip Fracture: Survival Outcomes and Multivariate Analysis in a Chilean Cohort.Journal of clinical medicine · 2025Article
- Hospital-acquired COVID-19 and its effect on length of stay and mortality in orthopedic admissions: A matched cohort study.Journal of orthopaedics · 2025Article
- Effect of Body Composition on Supine Pressure Distribution in Bed: A Comparison Between Young and Older Adults.Cureus · 2025Article
- Quality of life and symptom burden among hematologic malignancy patients undergoing CAR-T therapy: a cross-sectional study.Scientific reports · 2025Article
- Delayed ambulation in adult patients after major abdominal surgery in Northwest Ethiopia: a multicenter prospective follow up study.Scientific reports · 2025Article
- Care of the bedridden patient.Singapore medical journal · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe the association between major complications of immobility (pressure ulcer, pneumonia, deep vein thrombosis and urinary tract infection) during hospitalization and the patients' health-related quality of life after discharge.
methodsThe data were obtained from a multi-center study conducted in 2015. Complications of immobility during hospitalization was measured by case report form and quality of life after discharge was measured using the EQ-5D scale by telephone interview. Multilevel mixed-effects models were used to explore the association of complications and responses in the EQ-5D dimensions after controlling for important covariates.
resultsAmong the 20,515 bedridden patients, 2,601(12.72%) patients experienced at least one of the major complications of immobility during hospitalization, including pressure ulcer (527, 2.57%), deep vein thrombosis (343, 1.67%), pneumonia (1647, 8.16%), and urinary tract infection (265, 1.29%). Patients with any of the four complications during hospitalization reported more problems in all EQ-5D dimensions except for pain/discomfort, and had lower mean EQ-VAS scores than those without any complications. The four complications all showed significant associations with the proportion of reported problems in certain dimensions after adjustment for confounding variables.
conclusionsMajor complications of immobility were significantly associated with reduced health related quality of life. Prevention of complications is critical to reduce the burden of decreased quality of life for bedridden patients.
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