Evidence map›Paper›PMID 30312140›Full record

ArticlePhysiological genomics2018

Comparative gene array analyses of severe elastic fiber defects in late embryonic and newborn mouse aorta.

Marius Catalin Staiculescu, Austin J Cocciolone, Jesse D Procknow, Jungsil Kim, Jessica E Wagenseil

Open access · bronzeAbstract read
In one paragraph

Article in Physiological genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Mechanics and mechanobiology of arterial development.Biomechanics and modeling in mechanobiology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Collagen VIII in vascular diseases.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Review
  8. Article
  9. Elastin, arterial mechanics, and stenosis.American journal of physiology. Cell physiology · 2022
    Review
  10. Review
  11. Bioreactors for Vocal Fold Tissue Engineering.Tissue engineering. Part B, Reviews · 2022
    Review
  12. Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin.Journal of the mechanical behavior of biomedical materials · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marius Catalin StaiculescuDepartment of Mechanical Engineering and Materials Science, Washington University , St. Louis, Missouri.
Austin J CoccioloneDepartment of Biomedical Engineering, Washington University , St. Louis, Missouri.
Jesse D ProcknowDepartment of Mechanical Engineering and Materials Science, Washington University , St. Louis, Missouri.
Jungsil KimDepartment of Mechanical Engineering and Materials Science, Washington University , St. Louis, Missouri.
Jessica E WagenseilDepartment of Mechanical Engineering and Materials Science, Washington University , St. Louis, Missouri.
Washington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WOMEN'S HEALTH AGENDAU01AI025903 · NIAID · WASHINGTON UNIVERSITY · PI CLIFFORD, DAVID B · 1987 to 2006
$12.5M
VESSEL STIFFENING, HYPERTENSION, AND VASCULAR EXTRACELLULAR MATRIXR01HL105314 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P., WAGENSEIL, JESSICA · 2010 to 2018
$3.2M
BIOMECHANICAL FACTORS IN CONGENITAL VASCULAR DISEASER01HL115560 · NHLBI · WASHINGTON UNIVERSITY · PI WAGENSEIL, JESSICA · 2012 to 2015
$1.5M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NHLBI NIH HHS R01 HL105314NHLBI NIH HHS R01 HL115560NIAID NIH HHS U01 AI025903
6 · The paper itself

Abstract

Elastic fibers provide reversible elasticity to the large arteries and are assembled during development when hemodynamic forces are increasing. Mutations in elastic fiber genes are associated with cardiovascular disease. Mice lacking expression of the elastic fiber genes elastin ( Eln

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsAnimals, NewbornAortaAortic AneurysmArteriesCollagen Type VIIIDisease Models, AnimalElastic TissueElastinExtracellular Matrix ProteinsFemaleInsulin-Like Growth Factor Binding Protein 2Joint InstabilityMice, KnockoutOligonucleotide Array Sequence AnalysisCollagen Type VIIIEfemp2 protein, mouseElastinExtracellular Matrix ProteinsInsulin-Like Growth Factor Binding Protein 2Protein-Lysine 6-OxidaseThrombospondin 1cardiovascularcollagenelastinextracellular matrixsmooth muscle cell

Identifiers

PMID30312140
PMCPMC6293116
OpenAlexW2896977034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.