Evidence map›Paper›PMID 30311777›Full record

ArticleAIDS patient care and STDs2018

Limited Knowledge and Mixed Interest in Pre-Exposure Prophylaxis for HIV Prevention Among People Who Inject Drugs.

Angela R Bazzi, Dea L Biancarelli, Ellen Childs, Mari-Lynn Drainoni, Alberto Edeza, Peter Salhaney, Matthew J Mimiaga, Katie B Biello

3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 84 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04521920 nacompletednot on this mapstarted 2020, after this paper: background citation

Providing Comprehensive Harm Reduction Via Telemedicine for PWID Using Syringe Services Programs: a Feasibility Study

TypeinterventionalSponsorDuke UniversityRan2020 to 2021Enrolled17ConditionsOpioid Use, Opioid-use Disorder, Risk Reduction, HivArmsSuboxone, PrEP
NCT05977881 nacompletednot on this mapstarted 2023, after this paper: background citation

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2026Enrolled493ConditionsHIV InfectionsArmsCHECKIT!
NCT06025435 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

SAIA-SSP-HIV: a Systems Analysis and Improvement Approach to Optimizing HIV Service Delivery in Syringe Services Programs

TypeinterventionalSponsorUniversity of California, San DiegoRan2023 to 2027Enrolled32ConditionsHIV InfectionsArmsSAIA-HIV-SSP
3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Angela R Bazzi1 Department of Community Health Sciences, Boston University School of Public Health , Boston, Massachusetts.
Dea L Biancarelli2 Department of Health Law, Policy and Management, Boston University School of Public Health , Boston, Massachusetts.
Ellen Childs2 Department of Health Law, Policy and Management, Boston University School of Public Health , Boston, Massachusetts.
Mari-Lynn Drainoni2 Department of Health Law, Policy and Management, Boston University School of Public Health , Boston, Massachusetts.
Alberto Edeza6 Center for Health Equity Research, Brown University , Providence, Rhode Island.
Peter Salhaney6 Center for Health Equity Research, Brown University , Providence, Rhode Island.
Matthew J Mimiaga6 Center for Health Equity Research, Brown University , Providence, Rhode Island.
Katie B Biello6 Center for Health Equity Research, Brown University , Providence, Rhode Island.
Boston University · USBrown University · USFenway Health · USEdith Nourse Rogers Memorial Veterans Hospital · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Preventing HIV infection among people who inject drugs during COVID-19K01DA043412 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZZI, ANGELA ROBERTSON · 2017 to 2021
$934k
NIAID NIH HHS P30 AI042853NIDA NIH HHS K01 DA043412
6 · The paper itself

Abstract

People who inject drugs (PWID) experience sexual and injection-related HIV risks, but uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among PWID has been low. Improving PrEP uptake in this population will require understanding of PrEP knowledge and interest. In 2017, we conducted in-depth, semistructured interviews with HIV-uninfected PWID and key informants (PrEP and harm reduction providers) in the US Northeast. Thematic analysis of coded data explored PrEP knowledge and the factors that influence PrEP interest. Among PWID (n = 33), median age was 36 years, 55% were male, 67% were white, and 24% identified as Hispanic/Latino. Accurate PrEP knowledge among PWID was low, which key informants (n = 12) attributed to PrEP marketing focused on other risk populations, as well as healthcare providers' lack of time and unwillingness to discuss PrEP with PWID. There was a discrepancy between self-reported HIV risk behaviors, which were common, and HIV risk perceptions, which varied and strongly influenced PrEP interest. Most PWID and key informants thought that PrEP would be most beneficial for those who shared syringes, used discarded syringes, engaged in transactional sex, or were homeless. Improving uptake of PrEP for HIV prevention among high-risk PWID will require education to increase PrEP knowledge and addressing factors that negatively influence PrEP interest such as perceptions regarding low HIV risk and the process for obtaining PrEP. This may require specialized PrEP marketing and outreach efforts and improved capacity of healthcare providers to effectively assess HIV risk (and perceptions) and communicate the benefits of PrEP to at-risk PWID.

Indexed as

Harm ReductionAdultAnti-HIV AgentsAttitude of Health PersonnelDrug UsersFemaleHIV InfectionsHumansInterviews as TopicMaleMiddle AgedNeedle SharingPerceptionPre-Exposure ProphylaxisQualitative ResearchSexual BehaviorAnti-HIV Agentsharm reductionHIV infectionsneedle sharingpre-exposure prophylaxisrisk takingsexual behavior

Identifiers

PMID30311777
PMCPMC6300044
OpenAlexW2897426099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.