Evidence map›Paper›PMID 30311671›Full record

ArticleNeurourology and urodynamics2019

Aging increases the expression of vasopressin receptors in both the kidney and urinary bladder.

Lori A Birder, Amanda S Wolf-Johnston, Edwin K Jackson, Alan J Wein, Roger Dmochowski

Open access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dysregulation of the fluid homeostasis system by aging.bioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Complementary Role of Oxytocin and Vasopressin in Cardiovascular Regulation.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lori A BirderUniversity of Pittsburgh School of Medicine, Department of Medicine, Pittsburgh, Pennsylvania.ORCID 0000-0002-3393-2256
Amanda S Wolf-JohnstonUniversity of Pittsburgh School of Medicine, Department of Medicine, Pittsburgh, Pennsylvania.
Edwin K JacksonUniversity of Pittsburgh School of Medicine, Department of Pharmacology and Chemical Biology, Pittsburgh, Pennsylvania.
Alan J WeinUniversity of Pennsylvania Perelman School of Medicine, Division of Urology, Philadelphia, Pennsylvania.
Roger DmochowskiVanderbilt University Medical Center, Department of Urology, Nashville, Tennessee.ORCID 0000-0002-9838-9178
University of Pittsburgh · USUniversity of Pennsylvania · USVanderbilt University Medical Center · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Adenosine in Renal Sympathetic NeurotransmissionR01DK091190 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2011 to 2020
$3.4M
Bladder Mucosal Dysfunction During AgingR01AG056944 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APODACA, GERARD L, BIRDER, LORI A · 2018 to 2022
$3.2M
Nitric Oxide in Bladder Neural-Epithelial SignalingR37DK054824 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A · 2007 to 2016
$3.0M
Role of Purine Dysregulation in the Underactive BladderR56AG063753 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, JACKSON, EDWIN KERRY · 2019 to 2019
$691k
NIA NIH HHS R01 AG056944NIA NIH HHS R56 AG063753NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK091190NIDDK NIH HHS R37 DK054824
6 · The paper itself

Abstract

aimsThe goal of this study was to determine whether aging effects the expression of V

methodsUBM and kidneys were obtained from young (3 months-of-age) and old (25-30 months-of-age) female Fisher 344 rats. Tissue samples were analyzed by western blotting for V

resultsV

conclusionsV

Indexed as

AgingAnimalsFemaleGene ExpressionKidneyRatsRats, Inbred F344Receptors, VasopressinUrinary BladderVasopressinsReceptors, VasopressinVasopressinsaquaporinsbladder mucosanocturiaolder adults

Identifiers

PMID30311671
PMCPMC9839378
OpenAlexW2895872098

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.