Evidence map›Paper›PMID 30311451›Full record

ArticleCNS neuroscience & therapeutics2019

Oxytocin receptor gene variants are associated with emotion recognition and resilience, but not with false-belief reasoning performance in healthy young Korean volunteers.

Hae Won Kim, Jee In Kang, Suk Kyoon An, Se Joo Kim

Open access · bronzeAbstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Neurobiological Bases of Social Networks.Frontiers in psychology · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hae Won KimDepartment of Medical Education, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-9321-8361
Jee In KangInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-2818-7183
Suk Kyoon AnInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0003-4576-6184
Se Joo KimInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-5438-8210
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsA growing body of literature has indicated that oxytocin is associated with several domains of social cognition and behavior. Nevertheless, the effects of oxytocin receptor gene (OXTR) polymorphisms on social phenotypes remain unclear. Therefore, we aimed to explore the genetic influence of OXTR variants on social cognition (social perception and theory of mind) and resilience in healthy individuals.

methodsWe examined the influence of 10 common OXTR variants on social cognitive abilities, including facial emotion recognition and theory of mind, and trait resilience in 264 unrelated, healthy participants.

resultsWe found a significant association between the A-C haplotype at rs237887-rs2268490 and facial affect recognition. In addition, the single marker rs2254298 was significantly associated with participants' scores on the Connor-Davidson Resilience Scale. In contrast, variations in OXTR did not affect participants' performance on the false-belief reasoning task.

conclusionsSingle makers or haplotypes at OXTR may contribute to individual differences in facial emotion recognition and psychological resilience.

Indexed as

Resilience, PsychologicalAdolescentAdultCultureEmotionsFacial ExpressionFemaleGenetic VariationHumansMalePolymorphism, Single NucleotidePsychomotor PerformanceReceptors, OxytocinRecognition, PsychologyRepublic of KoreaYoung AdultOXTR protein, humanReceptors, Oxytocinemotion recognitionfalse-belief reasoningoxytocin receptor generesiliencetheory of mind

Identifiers

PMID30311451
PMCPMC6488914
OpenAlexW2896494100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.