ArticleBrain and behavior2018
Clinical and imaging characteristics of PFO-related stroke with different amounts of right-to-left shunt.
Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patent Foramen Ovale in Cryptogenic Ischemic Stroke: Direct Cause, Risk Factor, or Incidental Finding?Frontiers in neurology · 2020Pooled it
- A whole-exome sequencing study of patent foramen ovale: investigating genetic variants and their association with cardiovascular disorders.Frontiers in genetics · 2024Article
- Percutaneous Patent Foramen Ovale Closure: Stroke and Beyond.Current cardiology reviews · 2024Review
- PFO-spectrum disorder: two different cerebrovascular diseases in patients with PFO as detected by AI brain imaging software.Frontiers in neurology · 2024Article
- The predictive value of abnormal electrocardiogram for patent foramen ovale: A retrospective study.Clinical cardiology · 2023Article
- Potential Embolic Sources in Embolic Stroke of Undetermined Source Patients with Patent Foramen Ovale.Cerebrovascular diseases (Basel, Switzerland) · 2023Article
- Recent progress in patent foramen ovale and related neurological diseases: A narrative review.Frontiers in neurology · 2023Review
- Percutaneous Patent Foramen Ovale Closure in Patients with Cryptogenic Stroke or Transient Ischemic Attack: A Retrospective Study.BioMed research international · 2022Article
- Pathogeneses and Imaging Features of Cerebral White Matter Lesions of Vascular Origins.Aging and disease · 2021Review
- Risk of Stroke in Patients With Patent Foramen Ovale Who Had Pulmonary Embolism.Journal of clinical medicine research · 2020Article
- The Correlation Between Migraine and Patent Foramen Ovale.Frontiers in neurology · 2020Review
- Posterior circulation ischemic stroke-a review part II: imaging and acute treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Review
- Clinical and imaging characteristics of PFO-related stroke with different amounts of right-to-left shunt.Brain and behavior · 2018Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionRight-to-left shunt (RLS) induced by a patent foramen ovale (PFO) is associated with an increased risk of cryptogenic stroke (CS). However, little is known about the relationship between the amount of RLS and the stroke pattern. In this study, we aimed to evaluate the distinct clinical features of PFO-related CS in different RLS degrees resulting from PFO.
methodsThis is a cohort study of 222 CS patients admitted to the Tongji Hospital from 1st May 2014 to 31st April 2017. All patients underwent contrast transcranial Doppler examination. And then, 121 (54.5%) were classified as non-RLS group, while 76 (34.2%) were classified as mild RLS group and 25 (11.3%) were large RLS group according to the number of micro-emboli signals. The groups were compared with respect to their clinical and neuroimaging characteristics.
resultsIn terms of risk factors of stroke, the prevalence of hypertension was lower in mild group (p = 0.002). Regarding the infarct patterns in different CS patients, we found that the multiple cortical lesions were more frequently observed (p<0.001) with increasing RLS in DWI. Moreover, there was a rising trend in the proportion of small lesions (≤1 cm) with an increasing RLS (p < 0.01). And as RLS increased, the posterior circulation was more likely to be influenced (p < 0.05). In addition, the serum cholesterol concentration was lower in the large RLS group, compared to the non-RLS group (p = 0.003) and mild RLS group (p = 0.008). While the mean platelet volume (MPV) in mild group was significantly higher than that of non-RLS group (p = 0.013).
conclusionPatients with larger RLS show more infarction in posterior circulation, higher frequency of small lesions or multiple cortical lesions. The results of our study indicate that the infarct patterns might be a clue of PFO-related stroke.
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