Evidence map›Paper›PMID 30311171›Full record

Observational studyEndocrine2019

Effects of dehydroepiandrosterone (DHEA) supplementation on sexual function in premenopausal infertile women.

Vitaly A Kushnir, Sarah K Darmon, David H Barad, Andrea Weghofer, Norbert Gleicher

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Vitaly A KushnirThe Center for Human Reproduction, New York, NY, USA. vkushnir@thechr.com.
Sarah K DarmonThe Center for Human Reproduction, New York, NY, USA.
David H BaradThe Center for Human Reproduction, New York, NY, USA.
Andrea WeghoferThe Center for Human Reproduction, New York, NY, USA.
Norbert GleicherThe Center for Human Reproduction, New York, NY, USA.
Center for Human Reproduction · USFoundation for Reproductive Medicine · USMedical University of Vienna · AT

Funding

Center for Human Reproduction (CHR) n/aFoundation for Reproductive Medicine (FRM) n/a
6 · The paper itself

Abstract

purposeTo investigate the effects of dehydroepiandrosterone (DHEA) supplementation on female sexual function in premenopausal infertile women of advanced ages.

methodsThis observational study was conducted in an academically affiliated private fertility center. Patients included 87 premenopausal infertile women, 50 of whom completed the study including the Female Sexual Function Index (FSFI) questionnaires and comprehensive endocrine evaluation before and 4-8 weeks after initiating 25 mg of oral micronized DHEA TID.

resultsAge of patients was 41.1 ± 4.2 years, BMI 24.4 ± 6.1 kg/m

conclusionsThis uncontrolled observational study implies that supplementation with DHEA improves sexual function in older premenopausal women with low baseline FSFI scores.

Indexed as

AdultDehydroepiandrosteroneFemaleHumansInfertility, FemaleMiddle AgedPremenopauseSexual BehaviorDehydroepiandrosteroneAndrogensDehydroepiandrosterone (DHEA)Female sexual functionHormone statusInfertility

Identifiers

PMID30311171
OpenAlexW2896581395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.