Evidence map›Paper›PMID 30311100›Full record

ArticleVirologica Sinica2018

Countrywide Survey for MERS-Coronavirus Antibodies in Dromedaries and Humans in Pakistan.

Ali Zohaib, Muhammad Saqib, Muhammad Ammar Athar, Jing Chen, Awais-Ur-Rahman Sial, Saeed Khan, Zeeshan Taj, Halima Sadia, Usman Tahir, Muhammad Haleem Tayyab and 17 more

Open access · bronzeAbstract read
In one paragraph

Article in Virologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  14. Middle East respiratory syndrome coronavirus (MERS-CoV) neutralising antibodies in a high-risk human population, Morocco, November 2017 to January 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 12 institutions in 3 countries.

Ali ZohaibCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Muhammad SaqibFaculty of Veterinary Medicine, University of Agriculture, Faisalabad, 38040, Pakistan.
Muhammad Ammar AtharLaboratory of Cancer Biomarkers and Liquid Biopsy, College of Pharmacy, Henan University, Henan, 475004, China.
Jing ChenCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Awais-Ur-Rahman SialDepartment of Clinical Studies, Faculty of Veterinary and Animal Sciences, PMAS-Arid Agriculture University, Rawalpindi, 46000, Pakistan.
Saeed KhanDow University of Health Science, Karachi, 74200, Pakistan.
Zeeshan TajDepartment of Microbiology, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Halima SadiaLivestock and Dairy Development Department (L&DD), Lahore, 54000, Pakistan.
Usman TahirLivestock and Dairy Development Department (L&DD), Lahore, 54000, Pakistan.
Muhammad Haleem TayyabFaculty of Veterinary Medicine, University of Agriculture, Faisalabad, 38040, Pakistan.
Muhammad Asif QureshiDow University of Health Science, Karachi, 74200, Pakistan.
Muhammad Khalid MansoorCollege of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Muhammad Ahsan NaeemState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Bing-Jie HuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Bilal Ahmed KhanDow University of Health Science, Karachi, 74200, Pakistan.
Ikram Din UjjanLiaqat University of Medical and Health Science, Jamshoro, 76090, Pakistan.
Bei LiCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Wei ZhangCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Yun LuoCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Yan ZhuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Cecilia WaruhiuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Iahtasham KhanSection of Epidemiology and Public Health, Department of Clinical Sciences, University of Veterinary and Animal Sciences, Lahore subcampus, Jhang, 35200, Pakistan.
Xing-Lou YangCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Muhammad Sohail SajidFaculty of Veterinary Medicine, University of Agriculture, Faisalabad, 38040, Pakistan.
Victor Max CormanInstitute of Virology, Charité-Universitätsmedizin Berlin, Corporate member of Free University, Humboldt-University and Berlin Institute of Health, Berlin, 10117, Germany.
Bing YanCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Zheng-Li ShiCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. zlshi@wh.iov.cn.ORCID http://orcid.org/0000-0001-8089-163X
Chinese Academy of Sciences · CNDow University of Health Sciences · PKUniversity of Agriculture Faisalabad · PKGovernment of Khyber Pakhtunkhwa · PKGerman Center for Infection Research · DEGovernment College University, Faisalabad · PKHenan University · CNHuazhong Agricultural University · CNIslamia University of Bahawalpur · PKLiaquat University of Medical & Health Sciences · PKPir Mehr Ali Shah Arid Agriculture University · PKUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic pathogen capable of causing severe respiratory disease in humans. Although dromedary camels are considered as a major reservoir host, the MERS-CoV infection dynamics in camels are not fully understood. Through surveillance in Pakistan, nasal (n = 776) and serum (n = 1050) samples were collected from camels between November 2015 and February 2018. Samples were collected from animal markets, free-roaming herds and abattoirs. An in-house ELISA was developed to detect IgG against MERS-CoV. A total of 794 camels were found seropositive for MERS-CoV. Prevalence increased with the age and the highest seroprevalence was recorded in camels aged > 10 years (81.37%) followed by those aged 3.1-10 years (78.65%) and ≤ 3 years (58.19%). Higher prevalence was observed in female (78.13%) as compared to male (70.70%). Of the camel nasal swabs, 22 were found to be positive by RT-qPCR though with high Ct values. Moreover, 2,409 human serum samples were also collected from four provinces of Pakistan during 2016-2017. Among the sampled population, 840 humans were camel herders. Although we found a high rate of MERS-CoV antibody positive dromedaries (75.62%) in Pakistan, no neutralizing antibodies were detected in humans with and without contact to camels.

Indexed as

Middle East Respiratory Syndrome CoronavirusAnimalsAntibodies, NeutralizingAntibodies, ViralCamelusChildChild, PreschoolCoronavirus InfectionsCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayEpidemiological MonitoringFemaleHumansMaleNosePakistanAntibodies, NeutralizingAntibodies, ViralCamelHumanMiddle East Respiratory Syndrome Coronavirus (MERS-CoV)Pakistan

Identifiers

PMID30311100
PMCPMC6235758
OpenAlexW2896315070

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.