Evidence map›Paper›PMID 30311094›Full record

ReviewCurrent cardiology reports2018

Neural Mechanisms Linking Emotion with Cardiovascular Disease.

Thomas E Kraynak, Anna L Marsland, Peter J Gianaros

Abstract readReview
In one paragraph

Review in Current cardiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Socioeconomic status, prefrontal cortical volume, and cardiometabolic risk in early adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  7. Brain and cardiovascular responses to acute stress in remitted and recurrent late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Coping and emotion regulation: A conceptual and measurement scoping review.Canadian psychology = Psychologie canadienne · 2024
    Article
  14. Article
  15. Cortical and subcortical brain networks predict prevailing heart rate.bioRxiv : the preprint server for biology · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. The Role of Inflammation in Cardiovascular Disease.International journal of molecular sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas E KraynakDepartment of Psychology, University of Pittsburgh, 210 South Bouquet Street, Pittsburgh, PA, 15260, USA. tekraynak@pitt.edu.
Anna L MarslandDepartment of Psychology, University of Pittsburgh, 210 South Bouquet Street, Pittsburgh, PA, 15260, USA.
Peter J GianarosDepartment of Psychology, University of Pittsburgh, 210 South Bouquet Street, Pittsburgh, PA, 15260, USA.
University of Pittsburgh · US

Funding

CARDIOVASCULAR BEHAVIORAL MEDICINE RESEARCH TRAININGT32HL007560 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peter J Gianaros, REBECCA C THURSTON · 1985 to 2026
$11.3M
Neurobiological pathways linking stress and emotion to atherosclerosisR01HL089850 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GIANAROS, PETER J · 2008 to 2016
$4.7M
NHLBI NIH HHS R01 HL089850NHLBI NIH HHS T32 HL007560
6 · The paper itself

Abstract

purpose of reviewThe present review discusses brain circuits that are engaged by negative emotions and possibly linked to cardiovascular disease risk. It describes recent human brain imaging studies that relate activity in these brain circuits to emotional processes, peripheral physiology, preclinical pathophysiology, as well as clinical outcomes. RECENT

findingsNegative emotions and the regulation of negative emotions reliably engage several brain regions that cross-sectional and longitudinal brain imaging studies have associated with CVD risk markers and outcomes. These brain regions include the amygdala, anterior cingulate cortex, medial prefrontal cortex, and insula. Other studies have applied advanced statistical techniques to characterize multivariate patterns of brain activity and brain connectivity that associate with negative emotion and CVD-relevant peripheral physiology. Brain imaging studies on emotion and cardiovascular disease risk are expanding our understanding of the brain-body bases of psychosocial and behavioral risk for cardiovascular disease.

Indexed as

EmotionsAmygdalaCardiovascular DiseasesFunctional NeuroimagingHumansMagnetic Resonance ImagingNeural PathwaysPrefrontal CortexStress, PsychologicalAmygdalaBrain imagingEmotionEmotion regulationMedial prefrontal cortexStress

Identifiers

PMID30311094
PMCPMC6444345
OpenAlexW2896010431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.