Evidence map›Paper›PMID 30310653›Full record

ReviewToxicology research2018

Delayed death following paraquat poisoning: three case reports and a literature review.

Shahin Shadnia, Alireza Ebadollahi-Natanzi, Saeid Ahmadzadeh, Somayyeh Karami-Mohajeri, Yaghoub Pourshojaei, Hamid Reza Rahimi

Abstract readReview
In one paragraph

Review in Toxicology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Rare fatal poisoning through dermal exposure to paraquat.SAGE open medical case reports · 2022
    Article
  12. Article
  13. Article
  14. Cytoprotective Activity ofMolecules (Basel, Switzerland) · 2021
    Article
  15. Lanostane Triterpenoid Metabolites from aMolecules (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahin ShadniaToxicology Research Center , Excellence Center of Clinical Toxicology , Department of Clinical Toxicology , Loghman Hakim Hospital , School of Medicine , Shahid Beheshti University of Medical Sciences , Tehran , Iran.ORCID 0000-0002-9401-0781
Alireza Ebadollahi-NatanziMedicinal Plants Department , Imam Khomeini Higher Education Center , Agricultural Research , Education and Extension Organization (AREEO) , Karaj , Iran.ORCID 0000-0002-0749-3309
Saeid AhmadzadehPharmaceutics Research Center , Institute of Neuropharmacology , Kerman University of Medical Sciences , Kerman , Iran . Email: hamidrrt@yahoo.com ; Email: h_rahimi@kmu.ac.ir.ORCID 0000-0001-8574-9448
Somayyeh Karami-MohajeriDepartment of Toxicology & Pharmacology , Faculty of Pharmacy , Kerman University of Medical Sciences , Kerman , Iran.ORCID 0000-0001-6256-6550
Yaghoub PourshojaeiDepartment of Medicinal Chemistry , Faculty of Pharmacy , Kerman University of Medical Sciences , Kerman , Iran.ORCID 0000-0002-6994-7361
Hamid Reza RahimiPharmaceutics Research Center , Institute of Neuropharmacology , Kerman University of Medical Sciences , Kerman , Iran . Email: hamidrrt@yahoo.com ; Email: h_rahimi@kmu.ac.ir.ORCID 0000-0002-9014-802X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraquat (PQ) poisoning is principally reported in developing countries. However, most fatalities occur elsewhere due to the induction of multi-organ failure. PQ poisoning can hardly be managed by clinical practice, and no specific antidote has come into existence yet. Here three cases, including 17-, 20-, and 23-year-old men, who were poisoned with PQ, have been reported. Furthermore, the literature regarding biological mechanisms, clinical manifestation, and treatment of PQ-induced toxicity was reviewed. Patients who, either intentionally or accidentally, ingested PQ earlier were initially found to be stable at the emergency department (ED). Therefore, they were discharged from the hospital under a follow-up. However, after several days, the patients were referred to the hospital for the second time and despite cardiovascular resuscitation (CPR) efforts, they suddenly expired. The delayed death following exposure to PQ was reported for inducing gradual progressive pulmonary fibrosis, metabolic acidosis, neurotoxicity, renal failure, and liver injury in poisoned patients. Therefore, PQ-intoxicated patients should be supervised for up to several weeks, and kept in the hospital for a longer period of time. Clinical manifestations and laboratory findings are beneficial markers that act as useful predictors of PQ poisoning.

Identifiers

PMID30310653
PMCPMC6116805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.