ArticleChemical science2018
Size-dependent rate acceleration in the silylation of secondary alcohols: the bigger the faster.
Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 28 citations in OpenAlex.
- Size-Induced Inversion of Selectivity in the Acylation of 1,2-Diols.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- An asymmetric Salamo-based Zn complex supported on FeRSC advances · 2021Article
- The Size-Accelerated Kinetic Resolution of Secondary Alcohols.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Relative rates for the reaction of secondary alcohols carrying large aromatic moieties with silyl chlorides carrying equally large substituents have been determined in organic solvents. Introducing thoroughly matching pairs of big dispersion energy donor (DED) groups enhanced rate constants up to four times, notably depending on the hydrogen bond donor ability of the solvent. A linear correlation between computed dispersion energy contributions to the stability of the silyl ether products and experimental relative rate constants was found. These results indicate a cooperation between solvophobic effects and DED-groups in the kinetic control of silylation reactions.
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Registered trials
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