ArticleChemical science2018
Ring-opening hydroarylation of monosubstituted cyclopropanes enabled by hexafluoroisopropanol.
Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Hexafluoroisopropanol Mediated Ring-Opening Reactions of Epoxides with Indoles Under Catalyst-Free Conditions.Molecules (Basel, Switzerland) · 2026Article
- Switchable reactivity of homopropargylic alcohols towards γ-arylated ketones and α-arylated tetrahydrofurans in HFIP.Chemical science · 2026Article
- Programmable divergent electrochemical ring-opening multifunctionalization of strained rings.Nature chemistry · 2026Article
- Regioselective C3-H Alkylation of Imidazopyridines with Donor-Acceptor Cyclopropanes.The Journal of organic chemistry · 2023Article
- Hydroarylation of enamides enabled by HFIPChemical science · 2022Article
- Hexafluoroisopropanol: the magical solvent for Pd-catalyzed C-H activation.Chemical science · 2021Review
- Ring-opening 1,3-arylboration of arylcyclopropanes mediated by BClRSC advances · 2020Article
- Synthetically important ring opening reactions by alkoxybenzenes and alkoxynaphthalenes.RSC advances · 2020Review
- Photoredox-catalyzed oxo-amination of aryl cyclopropanes.Nature communications · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ring-opening hydroarylation of cyclopropanes is typically limited to substrates bearing a donor-acceptor motif. Here, the transformation is achieved for monosubstituted cyclopropanes by using catalytic Brønsted acid in hexafluoroisopropanol (HFIP) solvent, constituting a rare example where such cyclopropanes engage in intermolecular C-C bond formation. Branched products are obtained when electron-rich arylcyclopropanes react with a broad scope of arene nucleophiles in accord with a simple S
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Registered trials
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