Evidence map›Paper›PMID 30310540›Full record

ArticleWorld journal of hepatology2018

Chronic hepatitis B virus monoinfection at a university hospital in Zambia.

Michael J Vinikoor, Edford Sinkala, Annie Kanunga, Mutinta Muchimba, Bright Nsokolo, Roma Chilengi, Gilles Wandeler, Joseph Mulenga, Tina Chisenga, Debika Bhattacharya and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis.Liver international : official journal of the International Association for the Study of the Liver · 2021
    Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 4 countries.

Michael J VinikoorTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
Edford SinkalaTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
Annie KanungaTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
Mutinta MuchimbaTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
Bright NsokoloTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
Roma ChilengiCentre for Infectious Disease Research in Zambia, Lusaka 34681, Zambia.
Gilles WandelerDepartment of Infectious Diseases, Bern University Hospital, University of Bern, Bern 3012, Switzerland.
Joseph MulengaZambia National Blood Transfusion Service, Private Bag RW1X Ridgeway, Lusaka 50110, Zambia.
Tina ChisengaZambian Ministry of Health, Ndeke House, Lusaka 30205, Zambia.
Debika BhattacharyaDepartment of Medicine, University of California at Los Angeles, Los Angeles, CA 90035, United States.
Michael S SaagDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, United States.
Graham FosterBlizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London E1 2AT, United Kingdom.
Michael W FriedDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, United States.
Paul KellyTropical Gastroenterology and Nutrition Group, School of Medicine, University of Zambia, Lusaka 50110, Zambia.
University of Zambia · ZMTropical Gastroenterology & Nutrition group · ZMCentre for Infectious Disease Research in Zambia · ZMMinistry of Health · ZMQueen Mary University of London · GBUniversity Hospital of Bern · CHUniversity of Alabama at Birmingham · USUniversity of California, Los Angeles · USUniversity of North Carolina at Chapel Hill · US

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
Lamivudine and its Impact on Perinatal HBV Transmission in HIV/HBV CoinfectionR01AI100748 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BHATTACHARYA, DEBIKA · 2012 to 2016
$1.9M
Impact of HIV PMTCT Interventions on HIV/HBV Co-infected Women and Their InfantsR01HD085862 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BHATTACHARYA, DEBIKA · 2016 to 2018
$1.3M
NIAID NIH HHS R01 AI100748NIAID NIH HHS U01 AI069924NICHD NIH HHS R01 HD085862
6 · The paper itself

Abstract

aimTo characterize antiviral therapy eligibility among hepatitis B virus (HBV)-infected adults at a university hospital in Zambia.

methodsHepatitis B surface antigen-positive adults (

resultsThe median age was 33 years, 71.9% were men, and 30.9% were diagnosed with HBV through a clinically-driven test with the remainder identified

conclusionApproximately one in ten HBV-monoinfected Zambians were eligible for antivirals. Many had indeterminate phenotype and needed clinical follow-up.

Indexed as

AfricaHepatitis B virusLiver fibrosisTenofovirTreatment

Identifiers

PMID30310540
PMCPMC6177566
OpenAlexW2892513636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.