Evidence map›Paper›PMID 30310527›Full record

ArticleBiomicrofluidics2018

Oral mucosa-on-a-chip to assess layer-specific responses to bacteria and dental materials.

Christopher Rahimi, Benjamin Rahimi, Dominic Padova, Seyed A Rooholghodos, Diane R Bienek, Xiaolong Luo, Gili Kaufman, Christopher B Raub

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomicrofluidics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
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  9. Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  10. Review
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  12. Host-microbe-cancer interactions on-a-chip.Frontiers in bioengineering and biotechnology · 2025
    Review
  13. Article
  14. The oral-gut microbiome axis in health and disease.Nature reviews. Microbiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Christopher RahimiDepartment of Biomedical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.
Benjamin RahimiDepartment of Biomedical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.ORCID 0000-0001-6988-6557
Dominic PadovaDepartment of Biomedical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.
Seyed A RooholghodosDepartment of Mechanical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.
Diane R BienekADA Foundation, Volpe Research Center, 100 Bureau Drive, Stop #8546, Gaithersburg, Maryland 20899, USA.
Xiaolong LuoDepartment of Mechanical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.ORCID 0000-0002-9939-2766
Gili KaufmanADA Foundation, Volpe Research Center, 100 Bureau Drive, Stop #8546, Gaithersburg, Maryland 20899, USA.
Christopher B RaubDepartment of Biomedical Engineering, The Catholic University of America, 620 Michigan Avenue NE, Washington, District of Columbia 20064, USA.ORCID 0000-0001-9487-0979
Catholic University of America · USUniversity of America · USVolpe National Transportation Systems Center · US

Funding

ANTIMICROBIAL AND REMINERALIZING COMPOSITES FOR CLASS V RESTORATIONSR01DE026122 · NIDCR · AMERICAN DENTAL ASSOCIATION FOUNDATION · PI BIENEK, DIANE R · 2016 to 2020
$1.7M
NIDCR NIH HHS R01 DE026122
6 · The paper itself

Abstract

The human oral mucosa hosts a diverse microbiome and is exposed to potentially toxic biomaterials from dental restoratives. Mucosal health is partly determined by cell and tissue responses to challenges such as dental materials and pathogenic bacteria. An

Identifiers

PMID30310527
PMCPMC6158033
OpenAlexW2893962363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.