Evidence map›Paper›PMID 30310483›Full record

ReviewEuropean cardiology2014

Diabetes Mellitus and Heart Failure.

Dimitris Tousoulis, Evangelos Oikonomou, Gerasimos Siasos, Christodoulos Stefanadis

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Mechanistic insight into the role of cardiac-enriched microRNAs in diabetic heart injury.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Use of Digital Health Technology in Heart Failure and Diabetes: a Scoping Review.Journal of cardiovascular translational research · 2023
    Article
  14. Diabetes Mellitus and Heart Failure.Journal of clinical medicine · 2021
    Review
  15. Association of antecedent cardiovascular risk factor levels and trajectories with cardiovascular magnetic resonance-derived cardiac function and structure.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  16. Review
  17. Article
  18. Observational
  19. Cardiometabolic medicine: time to recognize a new clinical specialty?Cardiovascular endocrinology & metabolism · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dimitris Tousoulis1st Cardiology Department, University of Athens Medical School, "Hippokration" Hospital, Athens, Greece.
Evangelos Oikonomou1st Cardiology Department, University of Athens Medical School, "Hippokration" Hospital, Athens, Greece.
Gerasimos Siasos1st Cardiology Department, University of Athens Medical School, "Hippokration" Hospital, Athens, Greece.
Christodoulos Stefanadis1st Cardiology Department, University of Athens Medical School, "Hippokration" Hospital, Athens, Greece.
National and Kapodistrian University of Athens · GRHippocration General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus and heart failure are two multifaceted entities characterised by high morbidity and mortality. Early epidemiological and prospective studies have observed the frequent co-existence of both conditions. Importantly, diabetes mellitus can precipitate or worsen heart failure due to the accumulation of advanced glycation end products, oxidative stress, inflammatory status impairment, decay of intracellular calcium, changes in microRNAs expression, not to mention atherosclerosis progression and coronary artery disease. Heart failure also impairs glucose metabolism through less well-known mechanisms. Attention must especially be given in the treatment as there are frequently adverse interactions between the two diseases and novel agents against diabetic cardiomyopathy are under investigation. As several missing links still exist in the connection between heart failure and diabetes mellitus we will review, in this article, the most recent data underlying the interaction of them and provide an overview of the most important clinical perspectives.

Indexed as

Diabetes mellitusheart failureinflammationoxidative stresspathophysiologytreatment

Identifiers

PMID30310483
PMCPMC6159396
OpenAlexW2326574367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.